Protein Alignment Scr and abd-A

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_732176.1
• Gene: abd-A / 42037
• FlyBaseID: FBgn0000014
• Length: 590
• Species: Drosophila melanogaster
• Alignment Length: 622
• Identity: 166/622 - (26%)
• Similarity: 232/622 - (37%)
• Gaps: 201/622 - (32%)

  Fly     8 MSSYQFVNSLASCYPQ----------QMNPQQNHPGAGNSSAGGSGGGAGGSGGVVPSGGTNGGQ 62
            ||.:.| :|:...|||          ...|..:...|..::...:...|..|.....|...|...
  Fly     1 MSKFVF-DSMLPKYPQFQPFISSHHLTTTPPNSSSAAVAAALAAAAASASASVSASSSSNNNSSN 64

  Fly    63 GSAGAATPGANDYFPAAAAYTPN----------LYPNTPQAHYANQAAYG--GQGNPDMVDYTQL 115
            ..||:.|...|:...:.::.:.|          |.|:....| ..|:.:.  ...:|....:.|:
  Fly    65 TIAGSNTSNTNNSSSSPSSSSNNNSNLNLSGGSLSPSHLSQH-LGQSPHSPVSSSSPFQQHHPQV 128

  Fly   116 QPQRLLLQQQQ----QQQQQQHAHAAAAVAAQQQQQ-----------LAQQQHPQQQ-------- 157
            |.|.|..||||    ||||..|.:::.:.|.|.|||           :|...|..||
  Fly   129 QQQHLNHQQQQHLHHQQQQHHHQYSSLSAALQLQQQQHHISKLAAAAVASHGHAHQQLLLTPPSA 193

  Fly   158 QQQQQANISCKYANDPVTPGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISPKLSPS 222
            ...|..:.||       :|..|    .|||::.:.|.|.|                      ||.
  Fly   194 GNSQAGDSSC-------SPSPS----ASGSSSLHRSLNDN----------------------SPG 225

  Fly   223 SVVESVARSLNKGVLGGSLAAAAAAAG------------LNN---NHSG-SGVSGGPG------- 264
            |...|.:.|....|...:.||||||:.            ::|   :|.| ||::|..|
  Fly   226 SASASASASAASSVAAAAAAAAAAASSSFAIPTSKMYPYVSNHPSSHGGLSGMAGFTGLEDKSCS 290

  Fly   265 -----------NVNVP-----------MHSPGG-----------------GDSDSESDSGNEAGS 290
                       :::||           .|:...                 |::.::..||...|:
  Fly   291 RYTDTVMNSYQSMSVPASASAQFAQFYQHATAAASAVSAASAGAIGVDSLGNACTQPASGVMPGA 355

  Fly   291 SQNSGNGKKNPPQIYPWM----------KRVHLGTSTVNANGET----KRQRTSYTRYQTLELEK 341
            ....|.|..:.|: ||||          :||..|    :.||..    :|.|.:|||:|||||||
  Fly   356 GGAGGAGIADLPR-YPWMTLTDWMGSPFERVVCG----DFNGPNGCPRRRGRQTYTRFQTLELEK 415

  Fly   342 EFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKE-HKMASMNIVPYHMGPYGHPYHQF 405
            |||||.|||||||||||||||||||||||||||||||.||| ..:..:|             .|.
  Fly   416 EFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEIN-------------EQA 467

  Fly   406 DIHPSQFAHLSAXDAWHFSGTGXRLNQLYQEPYQTAAAASAASGYQSQDGGP------------- 457
            .....:...:.| :....:... ::.|  |:..|..........:|.|...|
  Fly   468 RRDREEQEKMKAQETMKSAQQNKQVQQ--QQQQQQQQQQQQQQQHQQQQQQPQDHHSIIAHNPGH 530

  Fly   458 -----IG------GGSVGVGGGAGGPGSLANGGSNGS 483
                 :|      |..:|||.|.||.|....||..|:
  Fly   531 LHHSVVGQNDLKLGLGMGVGVGVGGIGPGIGGGLGGN 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	48/55 (87%)
abd-A	NP_732176.1	Homeodomain	399..455	CDD:459649	48/55 (87%)
		Abdominal-A	456..478	CDD:403567	3/34 (9%)