Protein Alignment Scr and Rx

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_726006.3
• Gene: Rx / 37367
• FlyBaseID: FBgn0020617
• Length: 904
• Species: Drosophila melanogaster
• Alignment Length: 523
• Identity: 120/523 - (22%)
• Similarity: 177/523 - (33%)
• Gaps: 190/523 - (36%)

  Fly     1 MDPDCFAMSSYQFVNSLASCYPQQMNPQQN-HPGAGNSSAGGSG----GGA----GGSGGVVPSG 56
            :.|..|. |..|.:.:||:    |...||| |.....||..|:|    .||    ..:..|.||
  Fly   321 LPPSSFG-SHQQHLAALAA----QAQEQQNQHSKYAKSSPTGAGPPPPPGAYFMESQTAPVAPS- 379

  Fly    57 GTNGGQGSAGAATPGANDYFPAAAAYTPNLYPNTP--------------------QAHYANQAAY 101
            ..|..:.|..:|:....|...||........|.||                    :...||....
  Fly   380 QINYDERSMSSASDLEEDDDDAAKLQLDVTSPPTPSPRGQLAAKRKSAGVFCDDNEPKLANGQLP 444

  Fly   102 GGQGNPDMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVAAQQQQQLAQQQHPQQQQQQQQANIS 166
            ||...        ::|:.:   ::...|||.|.|       |||||  |||  ||||.|||....
  Fly   445 GGNYG--------IRPRSM---EEVHHQQQSHHH-------QQQQQ--QQQ--QQQQLQQQQGFQ 487

  Fly   167 CKYANDPVTPGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISPKLSPSSVVESVARS 231
            ..:.|       ||.|..:|::|:.:.....|.:|.||
  Fly   488 HDFRN-------SGNGNPNGNSNSGDHGERLNADSDSL--------------------------- 518

  Fly   232 LNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGN 296
                 :.||.|::......|::..|..::.|               ||.|....|.|
  Fly   519 -----VNGSCASSEDLNQTNSSEQGEKITSG---------------SDDEGQDDNCA-------- 555

  Fly   297 GKKNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHAL 361
                        |:.|            :|.||::|.||..|||:.|..:.|.....|.|:|..:
  Fly   556 ------------KKKH------------RRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKV 596

  Fly   362 CLTERQIKIWFQNRRMKWKKEHKMASMNI-------VPYHMG---------PY----------GH 400
            .|.|.::::||||||.||:::.|..|:.:       :|:.:|         |:          |.
  Fly   597 NLPEVRVQVWFQNRRAKWRRQEKSESLRLGLTHFTQLPHRLGCGASGLPVDPWLSPPLLSALPGF 661

  Fly   401 PYHQFDIHPSQFAHLSAXDAWHFSGTGXRLNQLYQEPYQTAAAASAASGYQSQDGGP----IGGG 461
            ..|...::||...                 ..|...|.....::.||.|:.....||    :|.|
  Fly   662 LSHPQTVYPSYLT-----------------PPLSLAPGNLTMSSLAAMGHHHAHNGPPPPHVGHG 709

  Fly   462 SVG 464
            ..|
  Fly   710 GHG 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	24/55 (44%)
Rx	NP_726006.3	Homeodomain	560..616	CDD:459649	24/55 (44%)
		OAR	876..892	CDD:461067