Protein Alignment Scr and en

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 331
• Identity: 99/331 - (29%)
• Similarity: 145/331 - (43%)
• Gaps: 73/331 - (22%)

  Fly   121 LLQQQQQQQQQQHAHAAAAVAAQQQQQ------LAQQQHPQQQQQQQQANISCKYANDPVTPGGS 179
            ||:..:|||    |.||||.||...::      .....:|:..::..|:.:....||..:.|..|
  Fly   223 LLEFSRQQQ----AAAAAATAAMMLERANFLNCFNPAAYPRIHEEIVQSRLRRSAANAVIPPPMS 283

  Fly   180 GGGGVSGSNNNNNSANS--------------------NNNNSQSLASPQDLSTRDISPKLSPSSV 224
              ..:|.:|...::..|                    .::::.|||||...|  :.|...|.|||
  Fly   284 --SKMSDANPEKSALGSLCKAVSQIGQPAAPTMTQPPLSSSASSLASPPPAS--NASTISSTSSV 344

  Fly   225 VESVARSLNKGVLGGSLAAAAAAAGLNNN------HSGSGV-SGGPGNVNVPMHSPGGGDSDSES 282
            ..|.:.|        |...::||:.||::      .||||| :..|....:|..|....||..||
  Fly   345 ATSSSSS--------SSGCSSAASSLNSSPSSRLGASGSGVNASSPQPQPIPPPSAVSRDSGMES 401

  Fly   283 --DSGNEAGSSQNSGNGKKN--PPQIY-----------PWMKRVHLGTSTVNANGETKRQRTSYT 332
              |:.:|.||:...| ||..  |..:|           |..:|........|   :.||.||:::
  Fly   402 SDDTRSETGSTTTEG-GKNEMWPAWVYCTRYSDRPSSGPRYRRPKQPKDKTN---DEKRPRTAFS 462

  Fly   333 RYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNIVPYHM-- 395
            ..|...|::||:.|||||.|||.:::..|.|.|.||||||||:|.|.||  ...|.|.:...:
  Fly   463 SEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKK--STGSKNPLALQLMA 525

  Fly   396 -GPYGH 400
             |.|.|
  Fly   526 QGLYNH 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	29/55 (53%)
en	NP_523700.2	Homeodomain	455..511	CDD:459649	29/55 (53%)
		Engrail_1_C_sig	512..542	CDD:431338	5/20 (25%)