Protein Alignment Scr and B-H2

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Alignment Length: 580
• Identity: 139/580 - (23%)
• Similarity: 220/580 - (37%)
• Gaps: 200/580 - (34%)

  Fly    70 PGANDYFPAAAAYTPNLYPNTPQAHYANQAAYGGQGNPDMVDYTQLQPQRLLLQQQQQQQQQQ-- 132
            ||.|.|  |.....|:|..:.|.||||                        :|||||||||||
  Fly   167 PGNNPY--AHHPMPPHLLAHFPPAHYA------------------------VLQQQQQQQQQQQH 205

  Fly   133 ------------------HAHAAAAVAAQQQQQLA----QQQHPQQQQQQQQANISCKYANDPVT 175
                              |.|......||....|:    ||.||........     :.:..|:.
  Fly   206 PHPHHLQLERERLEALHRHGHGLTGDPAQHLSHLSHLSHQQHHPHLHHPMHD-----ERSRSPLM 265

  Fly   176 PGGSGGGGVSGSNNNNNS---ANSNNNNSQSLASPQDLSTRDISPKLSPSSVVESVARSLNKGVL 237
            ....||.|.:.:||||||   :|:||||:.|                          .|.|..::
  Fly   266 LQQLGGNGGNNNNNNNNSSSASNNNNNNNNS--------------------------ASANSNII 304

  Fly   238 GGSLAAAAAAAGLNNNHSGSG--VSGGPGNVNVPMHSPGGGDSDSE-----SDSGNEAGSSQNSG 295
            .|:     :::..|||.||:|  :.||||:......:....||||:     .|.|:::..:.:|.
  Fly   305 SGN-----SSSSNNNNGSGNGNMLLGGPGSSISGDQASTIDDSDSDDCGGKDDDGDDSMKNGSSA 364

  Fly   296 NGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHA 360
            ||..:.          ||   :::.:.:.::.||::|.:|...|||.|...:||:.:.|:|:|:.
  Fly   365 NGDSSS----------HL---SLSLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANK 416

  Fly   361 LCLTERQIKIWFQNRRMKWKKEHKMA----------------------SMNIVPY-----HMGPY 398
            |.|::.|:|.|:||||.|||::..:.                      .::..||     ...|:
  Fly   417 LELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGATPYLSAWPYAAAAAAQSPH 481

  Fly   399 GHPYHQFDIHPSQFAHLSAXDAWHFSGT----------GXRLNQLYQEP-----------YQTAA 442
            |......||:..|.|..:| .......:          | .|..:...|           |..||
  Fly   482 GATPSAIDIYYRQAAAAAAMQKPSLPASYRMYQSSIPPGMSLPGMPAPPPPGAAPMLSGYYAAAA 546

  Fly   443 AASAASGYQSQDGGPIGGGSVGVGGGAGGPGSLANGGSNGSGPNSLFASAASSSQAPDCIKYPQE 507
            ||:|::|.|.|...|              |.:       ...|    |::.|::...||.:....
  Fly   547 AAAASAGAQQQQQQP--------------PAA-------SRSP----ATSQSANSEADCERTSSS 586

  Fly   508 FXSQVII------------RQQHQQQQDNSMDRNQERDLKLLLETDCEPD----PELQLE 551
            . .::|.            |::..:::|.  :|::|||::...|.:.|.|    .||.||
  Fly   587 SRQRLITPSPPLNPGSPPHRERINEEEDR--ERDEERDIERERERERERDEDDEEELALE 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	24/55 (44%)
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	24/55 (44%)