Protein Alignment Scr and HOXC4

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_055435.2
• Gene: HOXC4 / 3221
• HGNCID: 5126
• Length: 264
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 100/306 - (32%)
• Similarity: 131/306 - (42%)
• Gaps: 101/306 - (33%)

  Fly    88 PNTPQAHYANQAAYGGQGNPDMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVAAQQQQQLAQQQ 152
            |..|.....:|.:|..:.:|:....|             ::...||.|          |:|....
Human    15 PKFPPCEEYSQNSYIPEHSPEYYGRT-------------RESGFQHHH----------QELYPPP 56

  Fly   153 HPQQQQQQQQANISCKYANDPVTPGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISP 217
            .|:....::|  .||.....   ||.|.|.|.:      .:.:.:...||||..|..||....||
Human    57 PPRPSYPERQ--YSCTSLQG---PGNSRGHGPA------QAGHHHPEKSQSLCEPAPLSGASASP 110

  Fly   218 KLSPSSVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSES 282
            ..:|.:.                                                     |....
Human   111 SPAPPAC-----------------------------------------------------SQPAP 122

  Fly   283 DSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNAN---GETKRQRTSYTRYQTLELEKEFH 344
            |..:.|.|.|         |.:|||||::|:  ||||.|   ||.||.||:|||.|.||||||||
Human   123 DHPSSAASKQ---------PIVYPWMKKIHV--STVNPNYNGGEPKRSRTAYTRQQVLELEKEFH 176

  Fly   345 FNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNI 390
            :||||||||||||||:|||:|||||||||||||||||:|::.:..:
Human   177 YNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKV 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	48/55 (87%)
HOXC4	NP_055435.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..130		31/197 (16%)
		Antp-type hexapeptide	135..140		3/4 (75%)
		Homeodomain	157..213	CDD:459649	48/55 (87%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..264		1/9 (11%)