Protein Alignment Scr and HOXB8

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_076921.1
• Gene: HOXB8 / 3218
• HGNCID: 5119
• Length: 243
• Species: Homo sapiens
• Alignment Length: 228
• Identity: 84/228 - (36%)
• Similarity: 104/228 - (45%)
• Gaps: 65/228 - (28%)

  Fly   192 NSANSNNNNSQSL-------ASPQDLSTRDISPKL--SPSSVVESVARSLNKGVLGGSL------ 241
            ||..|.....:||       ...|||..|   |.:  .|||              |||.
Human     7 NSLFSKYKTGESLRPNYYDCGFAQDLGGR---PTVVYGPSS--------------GGSFQHPSQI 54

  Fly   242 ------AAAAAAAGLNNNHSGSGVSGGPGNV--NVPMHSP---GGGDSD----------SESDSG 285
                  .::.:.|....|.......|.|||.  ..|:...   |..|.|          :.|..|
Human    55 QEFYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLG 119

  Fly   286 NEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLT 350
            .||..|:.|    .:|.|::|||:        ..|....:|.|.:|:|||||||||||.||.|||
Human   120 EEAEGSEQS----PSPTQLFPWMR--------PQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLT 172

  Fly   351 RRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 383
            |:||||::|||.|||||:||||||||||||||:
Human   173 RKRRIEVSHALGLTERQVKIWFQNRRMKWKKEN 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	43/55 (78%)
HOXB8	NP_076921.1	Antp-type hexapeptide	134..139		2/4 (50%)
		Homeodomain	147..203	CDD:459649	43/55 (78%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..243		2/3 (67%)