DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scr and hoxb8a

DIOPT Version :9

Sequence 1:	NP_001368995.1	Gene:	Scr / 40833	FlyBaseID:	FBgn0003339	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	XP_005171620.1	Gene:	hoxb8a / 30343	ZFINID:	ZDB-GENE-990415-108	Length:	246	Species:	Danio rerio

Alignment Length:	160	Identity:	68/160 - (42%)
Similarity:	90/160 - (56%)	Gaps:	42/160 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 NHSGSGVSGGPGNVN---VPMH-SPGG-------------GDSDSE----SDS-------GNEAG 289
            :|..|.:|..|...:   |..| .||.             |..|::    ||.       |:|..
Zfish    59 HHGASTLSAAPYQQSPCAVTCHGEPGNFYGYDALQRQTLFGAQDADLVQYSDCKLATGGIGDETD 123

  Fly   290 SSQNSGNGKKNPPQIYPWMK-RVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRR 353
            :::.|    .:|.|::|||: :|..|         .:|.|.:|:|||||||||||.||.||||:|
Zfish   124 NTEQS----PSPTQLFPWMRPQVAAG---------RRRGRQTYSRYQTLELEKEFLFNPYLTRKR 175

  Fly   354 RIEIAHALCLTERQIKIWFQNRRMKWKKEH 383
            |||::|||.|||||:||||||||||||||:
Zfish   176 RIEVSHALGLTERQVKIWFQNRRMKWKKEN 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeobox	328..381	CDD:395001	42/52 (81%)
hoxb8a	XP_005171620.1	Homeobox	150..202	CDD:278475	41/51 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.810