Protein Alignment Scr and Hmx3

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001099772.1
• Gene: Hmx3 / 293537
• RGDID: 1559927
• Length: 356
• Species: Rattus norvegicus
• Alignment Length: 339
• Identity: 78/339 - (23%)
• Similarity: 107/339 - (31%)
• Gaps: 137/339 - (40%)

  Fly   205 ASPQDLSTRDISPKLSPSSVVESVARSLNKG----------------------VLGGSLAAAAAA 247
            |.|.....:..:||.||.|:     |:|..|                      ....:.||||||
  Rat    14 APPPQPPPQPPAPKESPFSI-----RNLLNGDHHRPPPKPQPPPRTLFAPASAAAAAAAAAAAAA 73

  Fly   248 AGLNNNHSGSGVSGGPGNV------------NVPMH--------------SPGGGD--------- 277
            .|.....:|..:| ..|::            .:|.|              :|.||.
  Rat    74 KGALEGAAGFALS-QVGDLAFPRFEIPAQRFALPAHYLERSPAWWYPYTLTPAGGHLPRPEASEK 137

  Fly   278 ---SDSESDSGNEAGS-------------------------SQNSGNGKKNPPQIYPWMKRVHLG 314
               .||...||.:..|                         ..:|..|||....: |......:|
  Rat   138 ALLRDSSPASGTDRDSPDPLLKADPDHKELDSKSPDEIILEESDSEEGKKEGEAV-PGAAGTTVG 201

  Fly   315 TSTVNANGE----------------TKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCL 363
            .:......|                .|:.||.::|.|..:||..|...|||:...|..:|.:|.|
  Rat   202 ATAATPGSEDWKAGADSPEKKPACRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHL 266

  Fly   364 TERQIKIWFQNRRMKWKKE-----------HKMASMNI-VP--YHMG--------------PYGH 400
            ||.|:||||||||.|||::           |..|...: ||  ||..              |...
  Rat   267 TETQVKIWFQNRRNKWKRQLAAELEAANLSHAAAQRIVRVPILYHENSAAEGAAAAAGAPVPVSQ 331

  Fly   401 PYHQFDIHPSQFAH 414
            |...|. ||..::|
  Rat   332 PLLTFP-HPVYYSH 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	28/55 (51%)
Hmx3	NP_001099772.1	Homeodomain	228..284	CDD:459649	28/55 (51%)