Protein Alignment Scr and VENTX

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_055283.1
• Gene: VENTX / 27287
• HGNCID: 13639
• Length: 258
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 70/265 - (26%)
• Similarity: 96/265 - (36%)
• Gaps: 67/265 - (25%)

  Fly   255 SGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNPPQI-----------YPWM 308
            |.|..||       |.|:|...|    ...|:..|..|.|  |.:.|||.           .|..
Human    24 SQSSCSG-------PTHTPRPAD----FSLGSLPGPGQTS--GAREPPQAVSIKEAAGSSNLPAP 75

  Fly   309 KRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQ 373
            :|...|.|.........|.||::|..|...||..|..::||:...|..:|..:.|:|.|||.|||
Human    76 ERTMAGLSKEPNTLRAPRVRTAFTMEQVRTLEGVFQHHQYLSPLERKRLAREMQLSEVQIKTWFQ 140

  Fly   374 NRRMKWKKEHKMASMNIVPYHMGPYGHPYHQFDIHPSQF-----------------AHLSAXDAW 421
            |||||.|::.:...::      .|:....|.    |..|                 |.||. .|.
Human   141 NRRMKHKRQMQDPQLH------SPFSGSLHA----PPAFYSTSSGLANGLQLLCPWAPLSGPQAL 195

  Fly   422 HF-SGTGXRLNQLYQEPYQTAAAASAASGYQSQDGGPIGGGSVGVGGGAGGPGSLANGGSNGSGP 485
            .. .|:. .|.|:.||...:|.|:..        |.|:       ......||..:.|.:..:||
Human   196 MLPPGSFWGLCQVAQEALASAGASCC--------GQPL-------ASHPPTPGRPSLGPALSTGP 245

  Fly   486 NSLFA 490
            ..|.|
Human   246 RGLCA 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	25/55 (45%)
VENTX	NP_055283.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..93		20/81 (25%)
		Homeodomain	93..148	CDD:459649	25/54 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..248		5/20 (25%)