Protein Alignment Scr and Tlx3

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_036012630.1
• Gene: Tlx3 / 27140
• MGIID: 1351209
• Length: 338
• Species: Mus musculus
• Alignment Length: 284
• Identity: 66/284 - (23%)
• Similarity: 104/284 - (36%)
• Gaps: 48/284 - (16%)

  Fly   105 GNPDMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVAAQQQQQLAQQQHPQQQQQQQQANISCKY 169
            |:|.....:..||.|....:.....|..|.|...:....|......|......:....|:    |
Mouse    30 GDPAASPPSPAQPFRPPRMEAPASAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGAS----Y 90

  Fly   170 ANDPVTPGGSGGGGVSGSNNNNNSANSNNNNSQSLASP-QDLSTRDISPKLSPSSVVESVARSLN 233
            ...|  |||..|....          |...:...|.:| :|..:..::..|:|:.|:...|....
Mouse    91 LGGP--PGGRPGAAYP----------SLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPL 143

  Fly   234 KGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGK 298
            .|.:...|.:|.                 |...:||..|..||.:....:|.......:.:....
Mouse   144 PGAVPPPLPSAL-----------------PAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAA 191

  Fly   299 KNPPQI-----YPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIA 358
            ..|..:     :|:..|         ...:.|:.|||::|.|..||||.||..:||....|..:|
Mouse   192 LTPFTVTRRIGHPYQNR---------TPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALA 247

  Fly   359 HALCLTERQIKIWFQNRRMKWKKE 382
            .:|.:|:.|:|.||||||.||:::
Mouse   248 KSLKMTDAQVKTWFQNRRTKWRRQ 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	28/55 (51%)
Tlx3	XP_036012630.1	PRK07764	<20..>109	CDD:236090	18/94 (19%)
		Homeodomain	214..270	CDD:459649	28/55 (51%)