Protein Alignment Scr and Prrx1

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_722543.1
• Gene: Prrx1 / 266813
• RGDID: 628884
• Length: 245
• Species: Rattus norvegicus
• Alignment Length: 188
• Identity: 45/188 - (23%)
• Similarity: 75/188 - (39%)
• Gaps: 47/188 - (25%)

  Fly   204 LASPQDLSTRDISPKLSPSSVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNV 268
            |.||.:|.|.......|.|.:::     |.:   .|.:.||.|...:  ..:|..:
  Rat    19 LDSPGNLDTLQAKKNFSVSHLLD-----LEE---AGDMVAAQADESV--GEAGRSL--------- 64

  Fly   269 PMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTR 333
             :.|||   ..|.||:..:.....||...||.                      :.:|.||::..
  Rat    65 -LESPG---LTSGSDTPQQDNDQLNSEEKKKR----------------------KQRRNRTTFNS 103

  Fly   334 YQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK--MASMN 389
            .|...||:.|....|.....|.::|..:.|||.::::||||||.|:::..:  :|:.|
  Rat   104 SQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKN 161

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	20/55 (36%)
Prrx1	NP_722543.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		3/4 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	54..103		14/85 (16%)
		Homeodomain	99..151	CDD:459649	18/51 (35%)
		OAR	219..235	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	222..235