Protein Alignment Scr and GBX1

DIOPT Version :9

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001092304.1
• Gene: GBX1 / 2636
• HGNCID: 4185
• Length: 363
• Species: Homo sapiens
• Alignment Length: 421
• Identity: 113/421 - (26%)
• Similarity: 159/421 - (37%)
• Gaps: 119/421 - (28%)

  Fly    35 GNSSAGGSGGGAGGSGGVVPSGGTNGGQGSA-------GAATPGANDY----FPAAAAYTP---- 84
            |.|:.||:|||.|            ||.|:|       |...|.:...    :|....|.|
Human     6 GGSAPGGNGGGGG------------GGPGTAFSIDSLIGPPPPRSGHLLYTGYPMFMPYRPLVLP 58

  Fly    85 ----------NLYPNTPQAHYANQ-----AAYGGQGNPDMVDYTQLQPQRLLLQQQQQQQQQQHA 134
                      .|.|..|.|.:|.:     .|..||..|.||..|...|............|:..|
Human    59 QALAPAPLPAGLPPLAPLASFAGRLTNTFCAGLGQAVPSMVALTTALPSFAEPPDAFYGPQELAA 123

  Fly   135 HAAAAVAAQQQQQLAQQQHPQQQQQQQQANISCKYANDPVTPGGSGGGGVSGSNNNNNSANSNNN 199
            .||||.|.      |.:.:|:...::.:..:..    |.:.|.
Human   124 AAAAAAAT------AARNNPEPGGRRPEGGLEA----DELLPA---------------------- 156

  Fly   200 NSQSLASPQDLSTRDISPKLSPSSVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPG 264
             .:.:|.|........| :..||...|....|.::..|.   |:|...||......||
Human   157 -REKVAEPPPPPPPHFS-ETFPSLPAEGKVYSSDEEKLE---ASAGDPAGSEQEEEGS------- 209

  Fly   265 NVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTST---------VNA 320
                      ||||:.:....:.||     |.|....|:  |.:|. .|||..         |.|
Human   210 ----------GGDSEDDGFLDSSAG-----GPGALLGPK--PKLKG-SLGTGAEEGAPVTAGVTA 256

  Fly   321 -NGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 384
             .|:::|:||::|..|.||||||||..:||:...|.:|||||.|:|.|:||||||||.|||   :
Human   257 PGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWK---R 318

  Fly   385 MASMNIVPYHMGPYGHP--YHQFDIHPSQFA 413
            :.:.|:......|..:|  .....:|.::||
Human   319 IKAGNVSSRSGEPVRNPKIVVPIPVHVNRFA 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeobox	328..381	CDD:395001	33/52 (63%)
GBX1	NP_001092304.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		12/36 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	128..265		38/198 (19%)
		Homeobox	264..317	CDD:306543	32/52 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810