Protein Alignment Scr and Msx2

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_037114.2
• Gene: Msx2 / 25483
• RGDID: 3116
• Length: 267
• Species: Rattus norvegicus
• Alignment Length: 252
• Identity: 65/252 - (25%)
• Similarity: 106/252 - (42%)
• Gaps: 50/252 - (19%)

  Fly   176 PGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISPKLSPS-----SVVESVARSLNKG 235
            ||...||...|:.......:|...:.::|.|.:.      .||.||:     :...:|.|.|
  Rat    24 PGPGPGGAEGGAEERRVKVSSLPFSVEALMSDKK------PPKESPAVPPDCASAGAVLRPL--- 79

  Fly   236 VLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKN 300
            :|.|.        |:.:.||       ||.:..|.      ::.|.....:|.|:......|:.:
  Rat    80 LLPGH--------GVRDAHS-------PGPLVKPF------ETASVKSENSEDGAPWIQEPGRYS 123

  Fly   301 PPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTE 365
            ||.     :.:...|.|:..:...::.||.:|..|.|.||::|...:||:...|.|.:.:|.|||
  Rat   124 PPP-----RHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTE 183

  Fly   366 RQIKIWFQNRRMKWKK-------EHKMASMNIVPYHMG---PYGHPYHQFDIHPSQF 412
            .|:||||||||.|.|:       :.|||:..::|....   |...|.....|:.:.:
  Rat   184 TQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSGFSLPFPINSPLQAASIYSASY 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	26/55 (47%)
Msx2	NP_037114.2	Homeodomain	143..199	CDD:459649	26/55 (47%)