Protein Alignment Scr and EVX1

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001980.1
• Gene: EVX1 / 2128
• HGNCID: 3506
• Length: 407
• Species: Homo sapiens
• Alignment Length: 403
• Identity: 109/403 - (27%)
• Similarity: 161/403 - (39%)
• Gaps: 125/403 - (31%)

  Fly   198 NNNSQSLASPQDLSTRDISPK--LSPSSVVESVARSLNKGVLGG--------SLAAAAAAAGLNN 252
            :|.|:::.||.......:.|:  |||.:|..:   :..:|  ||        .||.:||..|...
Human    25 SNLSEAVGSPLPEPPEKMVPRGCLSPRAVPPA---TRERG--GGGPEEEPVDGLAGSAAGPGAEP 84

  Fly   253 NHSGSGVSG-GPGNVNVPMHSPGG--GDSDSESD-------------------------SGNEA- 288
            ..:|:.:.| ||...:|...|..|  ..||:|||                         ||:||
Human    85 QVAGAAMLGPGPPAPSVDSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKGSGSEAL 149

  Fly   289 -----GSSQ----NSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFH 344
                 |.|:    |.|:|.....           ||...:|:.:.:|.||::||.|...|||||:
Human   150 VGSPNGGSETPKSNGGSGGGGSQ-----------GTLACSASDQMRRYRTAFTREQIARLEKEFY 203

  Fly   345 FNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNIVPYHMGPYGHPYHQFDIHP 409
            ...|::|.||.|:|.||.|.|..||:||||||||.|::....:          :.||     ..|
Human   204 RENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMT----------WPHP-----ADP 253

  Fly   410 SQFAHLSAXDAWHFSGTG-------XRLNQLYQEPYQTAAAASAASGYQSQDGGPI--------- 458
            :.:.::.:    |.:..|       ..|...|..|. ...||||||...|...|.:
Human   254 AFYTYMMS----HAAAAGGLPYPFPSHLPLPYYSPV-GLGAASAASAAASPFSGSLRPLDTFRVL 313

  Fly   459 -------------------GGGSVGVGGGAGGPGS-LA--NGGSNGSGPNSLFAS---AASSSQA 498
                               .|.:.|:|..||||.| ||  :|.:||..|.:..||   .||:|::
Human   314 SQPYPRPELLCAFRHPPLYPGPAHGLGASAGGPCSCLACHSGPANGLAPRAAAASDFTCASTSRS 378

  Fly   499 PDCIKYPQEFXSQ 511
            ...:.:.....|:
Human   379 DSFLTFAPSVLSK 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	31/55 (56%)
EVX1	NP_001980.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..120		27/95 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..179		11/52 (21%)
		Homeodomain	184..240	CDD:459649	31/55 (56%)