Protein Alignment Scr and Pitx3

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_006526827.1
• Gene: Pitx3 / 18742
• MGIID: 1100498
• Length: 388
• Species: Mus musculus
• Alignment Length: 300
• Identity: 83/300 - (27%)
• Similarity: 118/300 - (39%)
• Gaps: 66/300 - (22%)

  Fly   221 PSSVVESVAR-----SLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGD-SD 279
            ||:.:|...:     |:..|:||.:.|.:.|.     :.|.:|....|    :|.|...|.: ||
Mouse    71 PSTEIEDEIKRQRPPSMEFGLLGEAEARSPAL-----SLSDAGTPHPP----LPEHGCKGQEHSD 126

  Fly   280 SESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFH 344
            ||..|.:..|.|...|:.||                       :.:||||.:|..|..|||..|.
Mouse   127 SEKASASLPGGSPEDGSLKK-----------------------KQRRQRTHFTSQQLQELEATFQ 168

  Fly   345 FNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMN-------------IVPYHMG 396
            .|||.....|.|||....|||.::::||:|||.||:|..:.....             :.||...
Mouse   169 RNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGGFAAPLGGLVPPYEEV 233

  Fly   397 PYGHPYHQFDIHPSQFAHLSAXDAWHFSGTGXRLNQLYQEPYQTAAAASAASGYQSQDGGPIGGG 461
            ..|:.|..:.  |...|...|...:.|:.....:..|..:|..:..::.|||...|....|
Mouse   234 YPGYSYGNWP--PKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAP---- 292

  Fly   462 SVGVGGGAGGPGSLANGGSNGSGPNSLFASAASSSQAPDC 501
                 |...|||:|.  |..|:.|.  .|.||.||.|..|
Mouse   293 -----GTVPGPGALQ--GLGGAPPG--LAPAAVSSGAVSC 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	27/55 (49%)
Pitx3	XP_006526827.1	Homeodomain	149..205	CDD:459649	27/55 (49%)
		PTZ00395	<228..>322	CDD:185594	29/108 (27%)
		OAR	344..361	CDD:461067