Protein Alignment Scr and Pdx1

DIOPT Version :9

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_032840.1
• Gene: Pdx1 / 18609
• MGIID: 102851
• Length: 284
• Species: Mus musculus
• Alignment Length: 326
• Identity: 104/326 - (31%)
• Similarity: 128/326 - (39%)
• Gaps: 113/326 - (34%)

  Fly   201 SQSLASPQDLSTRDISPKLSPSSVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGN 265
            :.||.|.:..|..||||...|.                   .|:...||.:.:|
Mouse    51 TSSLGSLEQGSPPDISPYEVPP-------------------LASDDPAGAHLHH----------- 85

  Fly   266 VNVP-----MHSPGGGDSDSESDSGNEAGSSQNSGNGKKNPPQI---YPWMK--RVHL------- 313
             ::|     .|.|.|     ...:|.|.|       |.:.|.::   :||||  :.|.
Mouse    86 -HLPAQLGLAHPPPG-----PFPNGTEPG-------GLEEPNRVQLPFPWMKSTKAHAWKGQWAG 137

  Fly   314 GTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMK 378
            |..|.... |.||.||:|||.|.|||||||.||:|::|.||:|:|..|.||||.|||||||||||
Mouse   138 GAYTAEPE-ENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMK 201

  Fly   379 WKKEH--KMASMNIVPYHMGPYGHPYHQFDIHPSQFAHLSAXDAWHFSGTGXRLNQLYQEPYQTA 441
            ||||.  |.:|           |.|                      ||.| .     :||.|..
Mouse   202 WKKEEDKKRSS-----------GTP----------------------SGGGGG-----EEPEQDC 228

  Fly   442 AAASAASGYQSQDGGPIGGGSVGVGGGAGGPGSLANGGSNGSGPNSLFASAASSSQAPDCIKYPQ 506
            |   ..||.:.....|:     ...|||..||..| ....|..|:.|..|...||.||   ..||
Mouse   229 A---VTSGEELLAVPPL-----PPPGGAVPPGVPA-AVREGLLPSGLSVSPQPSSIAP---LRPQ 281

  Fly   507 E 507
            |
Mouse   282 E 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeobox	328..381	CDD:395001	38/52 (73%)
Pdx1	NP_032840.1	Transactivation domain. /evidence=ECO:0000250	13..73		9/40 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..116		22/107 (21%)
		Antp-type hexapeptide	119..124		2/4 (50%)
		Homeobox	150..203	CDD:278475	37/52 (71%)
		Nuclear localization signal	198..204		5/5 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	202..284		35/131 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810