Protein Alignment Scr and Nkx2-2

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_035049.1
• Gene: Nkx2-2 / 18088
• MGIID: 97347
• Length: 273
• Species: Mus musculus
• Alignment Length: 207
• Identity: 50/207 - (24%)
• Similarity: 76/207 - (36%)
• Gaps: 53/207 - (25%)

  Fly   209 DLSTRDISPKLSPSSVVESVARSLNKGVLG-GSLAAA---------------------AAAAGLN 251
            |.:..|.|....|....|....:...|.|| |:|.|.                     |:..||.
Mouse    20 DTNDEDGSVAEGPEEESEGPEPAKRAGPLGQGALDAVQSLPLKSPFYDSSDNPYTRWLASTEGLQ 84

  Fly   252 NNHSGSGVSGGPGNVNVPMHSPGGGDS-DSESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGT 315
            .:..|...|..|.:.:.....|...:| |::.::....|.:     |||
Mouse    85 YSLHGLAASAPPQDSSSKSPEPSADESPDNDKETQGGGGDA-----GKK---------------- 128

  Fly   316 STVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWK 380
                     :::|..:::.||.|||:.|...|||:...|..:|..:.||..|:||||||.|.|.|
Mouse   129 ---------RKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMK 184

  Fly   381 KEHKMASMNIVP 392
            :......|.:.|
Mouse   185 RARAEKGMEVTP 196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	23/55 (42%)
Nkx2-2	NP_035049.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		10/35 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..131		9/69 (13%)
		Homeodomain	129..185	CDD:459649	23/55 (42%)