Protein Alignment Scr and Msx1

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_034965.2
• Gene: Msx1 / 17701
• MGIID: 97168
• Length: 303
• Species: Mus musculus
• Alignment Length: 319
• Identity: 85/319 - (26%)
• Similarity: 125/319 - (39%)
• Gaps: 74/319 - (23%)

  Fly   176 PGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISPKLSPSSVVESVARSLNKGVLGGS 240
            |.|.|.|...|:.....:|...:...   |.|:      :...|.|.||...:|.....|.....
Mouse    24 PAGGGVGQAPGAAAATATAMGTDEEG---AKPK------VPASLLPFSVEALMADHRKPGAKESV 79

  Fly   241 LAAA--AAAAGLNNNHSGS--GVSGGPGNVNVPM---HSPGGGDSDSESDSGNEAGSSQNSGNGK 298
            |.|:  |.|||.:..|.|:  |..|.|...:.|.   |...||......|:..:|.|.:....
Mouse    80 LVASEGAQAAGGSVQHLGTRPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKLDR-- 142

  Fly   299 KNPPQIYPWM----------KRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRR 353
                  .|||          :|:.....|:..:...::.||.:|..|.|.||::|...:||:...
Mouse   143 ------TPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAE 201

  Fly   354 RIEIAHALCLTERQIKIWFQNRRMKWKK-------EHKMASMNIVP---YHMG-PYGHPYHQFDI 407
            |.|.:.:|.|||.|:||||||||.|.|:       :.|||:..::|   :.:. |.|.|
Mouse   202 RAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGP------ 260

  Fly   408 HPSQFAHLSAXDAWHFSGTGXRLNQLYQEPYQTAAAASAASGYQSQDGGPIGGGSVGVG 466
                .|..:| .|..:|.:|         |:|.||...|          |:|..:..||
Mouse   261 ----AAVAAAAGASLYSASG---------PFQRAALPVA----------PVGLYTAHVG 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	26/55 (47%)
Msx1	NP_034965.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	22..53		7/31 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	90..112		6/21 (29%)
		PTZ00449	<99..>248	CDD:185628	45/156 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	135..163		5/35 (14%)
		Homeodomain	173..229	CDD:459649	26/55 (47%)