DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Scr and egl-5

DIOPT Version :9

Sequence 1:	NP_001368995.1	Gene:	Scr / 40833	FlyBaseID:	FBgn0003339	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_001021166.1	Gene:	egl-5 / 176093	WormBaseID:	WBGene00001174	Length:	223	Species:	Caenorhabditis elegans

Alignment Length:	208	Identity:	59/208 - (28%)
Similarity:	88/208 - (42%)	Gaps:	51/208 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 GSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISPKLSPSSVVESVARSLNKGVLGGSLA 242
            ||.....:.::..::..::|::.|:..|..|.:...|.....:||:     ..||..|:    .|
Worm    11 GSSTASSAATSTTSSQPDANDHLSRLAAMTQGVGKEDPETSSTPST-----EASLYPGI----SA 66

  Fly   243 AAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNPPQIYP- 306
            |...:.|...|::..|...||...      ||.                          ||.||
Worm    67 AYMQSYGWPQNYNYFGQPLGPATF------PGW--------------------------PQCYPN 99

  Fly   307 --WMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIK 369
              |.....|..|       :|:.|.:|.||||..||.:|..:.|:::::|.|:.....||:||||
Worm   100 TAWPNYGELFAS-------SKKGRQTYQRYQTSVLEAKFQQSSYVSKKQREELRLQTQLTDRQIK 157

  Fly   370 IWFQNRRMKWKKE 382
            |||||||||.|||
Worm   158 IWFQNRRMKAKKE 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeobox	328..381	CDD:395001	27/52 (52%)
egl-5	NP_001021166.1	Homeobox	116..168	CDD:278475	27/51 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910