DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scr and mab-5

DIOPT Version :9

Sequence 1:	NP_001368995.1	Gene:	Scr / 40833	FlyBaseID:	FBgn0003339	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_498695.1	Gene:	mab-5 / 176091	WormBaseID:	WBGene00003102	Length:	200	Species:	Caenorhabditis elegans

Alignment Length:	170	Identity:	71/170 - (41%)
Similarity:	96/170 - (56%)	Gaps:	29/170 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 ARSLNKGVLGGSLAAAAAAAGLNN-------NHSGSGVSGGPGNVNVPMHSPGGGDSDSESDS-- 284
            ::|.:.|....:.::|||||..||       ||:         .:|...|....|..|:.|:.
Worm    23 SQSASSGTSASASSSAAAAAAANNLKTYELYNHT---------YMNNMKHMLAAGWMDNSSNPFA 78

  Fly   285 -GNEAGSSQNSGNGKKNPPQI----YPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFH 344
             .....:|.|.|..:.:.|.|    :||||   :|.:   ..||:||.|.:|:|.||||||||||
Worm    79 YNPLQATSANFGETRTSMPAISQPVFPWMK---MGGA---KGGESKRTRQTYSRSQTLELEKEFH 137

  Fly   345 FNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 384
            :::||||:||.||:..|.|||||:||||||||||.|||.|
Worm   138 YHKYLTRKRRQEISETLHLTERQVKIWFQNRRMKHKKEAK 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeobox	328..381	CDD:395001	37/52 (71%)
mab-5	NP_498695.1	Homeobox	120..173	CDD:278475	37/52 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166701
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45771
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.800