Protein Alignment Scr and Hoxd8

DIOPT Version :9

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_032302.2
• Gene: Hoxd8 / 15437
• MGIID: 96209
• Length: 289
• Species: Mus musculus
• Alignment Length: 398
• Identity: 107/398 - (26%)
• Similarity: 128/398 - (32%)
• Gaps: 166/398 - (41%)

  Fly     8 MSSYQFVNSLASCYPQQMNPQQNHPGAGNSSAGGSGGGAGGSGGVVPSGGTNGGQGSAGAATPGA 72
            |||| |||.|.|.|                                          .|.||...|
Mouse     1 MSSY-FVNPLYSKY------------------------------------------KAAAAAAAA 22

  Fly    73 NDYFPAAAAYTPNLY-----PNTPQAHYANQAAYGGQ--GNPDMVDYTQLQPQRLLLQQQQQQQQ 130
            .....|..|..|..|     |.....|.|....||..  |.|
Mouse    23 AAAAAAGEAINPTYYDCHFAPEVSGRHAAALQLYGNSAAGFP----------------------- 64

  Fly   131 QQHAHAAAAVAAQQQQQLAQQQHPQQQQQQQQANISCKYANDPVTPGGSGGGGVSGSNNNNNSAN 195
              |||                .||...               |..|.|.||||..|...:...|.
Mouse    65 --HAH----------------PHPHPH---------------PSPPPGCGGGGGPGPGQDYFHAG 96

  Fly   196 SNNNNSQSLASPQDLSTRDISPKLSPSSVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVS 260
            :.:..:...|:|.  ......|...|..               |.:|.          |......
Mouse    97 AGSPTAAYQAAPP--PPHPPPPPPPPPC---------------GGIAC----------HGEPAKF 134

  Fly   261 GGPGN---------------VNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNPPQIYPWMKR 310
            .|..|               |..|         |.:|.||| .|...:..|...:|.|::|||:
Mouse   135 YGYDNLQRQPIFTTQQEAELVQYP---------DCKSSSGN-IGEDPDHLNQSSSPSQMFPWMR- 188

  Fly   311 VHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNR 375
                   ..|....:|.|.:|:|:|||||||||.||.||||:||||::|.|.|||||:|||||||
Mouse   189 -------PQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHTLALTERQVKIWFQNR 246

  Fly   376 RMKWKKEH 383
            |||||||:
Mouse   247 RMKWKKEN 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeobox	328..381	CDD:395001	40/52 (77%)
Hoxd8	NP_032302.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	62..125		21/135 (16%)
		COG5576	139..272	CDD:227863	60/134 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..184		8/22 (36%)
		Antp-type hexapeptide	183..188		2/4 (50%)
		Homeobox	199..251	CDD:278475	39/51 (76%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	252..289		2/3 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810