Protein Alignment Scr and Hoxd4

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_034599.2
• Gene: Hoxd4 / 15436
• MGIID: 96208
• Length: 250
• Species: Mus musculus
• Alignment Length: 250
• Identity: 96/250 - (38%)
• Similarity: 120/250 - (48%)
• Gaps: 69/250 - (27%)

  Fly   210 LSTRDISPKLSPSSVVESVARSLNKGVLG--GSLAAAAAAAGLNNNHSG------------SGVS 260
            ::::.:.||..|..      ..|..|.||  |:....:.|.|.:...||            .|..
Mouse     8 VNSKYVDPKFPPCE------EYLQGGYLGEQGADYYGSGAQGADFQPSGLYPRPDFGEQPFGGGG 66

  Fly   261 GGPGNVNVPMHSPGGGDSDSESDSGNEAGS-------------------SQNS-------GNGKK 299
            .|||:.     .|..|.....|..|:..|:                   ||.:       |...|
Mouse    67 PGPGSA-----LPARGHGQEPSGPGSHYGAPGERCPAPPPAPLPGARACSQPTGPKQPPPGTALK 126

  Fly   300 NPPQIYPWMKRVHLGTSTVNAN---GETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHAL 361
            .|..:|||||:||:  ::||.|   ||.||.||:|||.|.|||||||||||||||||||||||.|
Mouse   127 QPAVVYPWMKKVHV--NSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTL 189

  Fly   362 CLTERQIKIWFQNRRMKWKKEHKM------------ASMNIVP-YHMGPYGHPYH 403
            ||:|||||||||||||||||:||:            .|.:..| .|:.|....:|
Mouse   190 CLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSCSSSAAPGQHLQPMAKDHH 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	49/55 (89%)
Hoxd4	NP_034599.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..126		17/99 (17%)
		Antp-type hexapeptide	131..136		3/4 (75%)
		Homeodomain	153..209	CDD:459649	49/55 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..250		6/34 (18%)