Protein Alignment Scr and Hoxc8

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_034596.1
• Gene: Hoxc8 / 15426
• MGIID: 96198
• Length: 242
• Species: Mus musculus
• Alignment Length: 214
• Identity: 79/214 - (36%)
• Similarity: 102/214 - (47%)
• Gaps: 53/214 - (24%)

  Fly   176 PGGSGGGGVSGSN------NNNNSANSNNNNSQSLASPQDLSTRDISPKLSPSSVVESVARSLNK 234
            ||||..|....|:      ::..|..||:...|   :|..||....:.|...   .|::.|.
Mouse    42 PGGSAPGFQHASHHVQDFFHHGTSGISNSGYQQ---NPCSLSCHGDASKFYG---YEALPRQ--- 97

  Fly   235 GVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKK 299
                 ||..|...|.:               |..|         |.:|.:...:...|...|...
Mouse    98 -----SLYGAQQEASV---------------VQYP---------DCKSSANTNSSEGQGHLNQNS 133

  Fly   300 NPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLT 364
            :|..::||| |.|       |.|. :..|.:|:|||||||||||.||.||||:||||::|||.||
Mouse   134 SPSLMFPWM-RPH-------APGR-RSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLT 189

  Fly   365 ERQIKIWFQNRRMKWKKEH 383
            |||:||||||||||||||:
Mouse   190 ERQVKIWFQNRRMKWKKEN 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	42/55 (76%)
Hoxc8	NP_034596.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..154		11/48 (23%)
		Antp-type hexapeptide	138..143		3/5 (60%)
		Homeodomain	150..206	CDD:459649	42/55 (76%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..242		2/3 (67%)