Protein Alignment Scr and Hoxc12

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_034593.1
• Gene: Hoxc12 / 15421
• MGIID: 96194
• Length: 280
• Species: Mus musculus
• Alignment Length: 351
• Identity: 83/351 - (23%)
• Similarity: 126/351 - (35%)
• Gaps: 145/351 - (41%)

  Fly    64 SAGAATPGANDY----------FPAAAAYTPNLYP----------NTP-------------QAHY 95
            ::||..||....          .|..:|...|.||          |.|             :.:|
Mouse    31 ASGAQLPGLPSLSYPRRDNVCSLPWPSAEPCNGYPQPYLGSPVSLNPPFGRTCELARVEDSKGYY 95

  Fly    96 ANQAAYGGQGNPDMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVAAQQQQQLAQQQHPQQQQQQ 160
            ....|.||.|.               |:::::.::......||.:      ||.....|.
Mouse    96 REPCAEGGGGG---------------LKREERGREPGAGPGAALL------QLEPSGPPA----- 134

  Fly   161 QQANISCKYANDPVTPGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISPKLSPSSVV 225
                :..||   ..|..|.||.|.:|..::..|.       |||.|
Mouse   135 ----LGFKY---DYTASGGGGDGSTGPPHDPPSC-------QSLES------------------- 166

  Fly   226 ESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEAGS 290
            :|.:..||:|                 |.|.|  :|.||::..|: :||||.|.|.:
Mouse   167 DSSSSLLNEG-----------------NKSAS--AGDPGSLVSPL-NPGGGLSASGA-------- 203

  Fly   291 SQNSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRI 355
                           ||.. :|         ..::::|..|::.|..|||.||..|.::||:||.
Mouse   204 ---------------PWYP-IH---------SRSRKKRKPYSKLQLAELEGEFLVNEFITRQRRR 243

  Fly   356 EIAHALCLTERQIKIWFQNRRMKWKK 381
            |::..|.|:::|:||||||||||.|:
Mouse   244 ELSDRLNLSDQQVKIWFQNRRMKKKR 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	27/55 (49%)
Hoxc12	NP_034593.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..212		44/228 (19%)
		Homeodomain	213..269	CDD:459649	27/55 (49%)