DRSC/TRiP Functional Genomics Resources

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Protein Alignment Scr and Hoxb8

DIOPT Version :9

Sequence 1:NP_001368995.1 Gene:Scr / 40833 FlyBaseID:FBgn0003339 Length:564 Species:Drosophila melanogaster
Sequence 2:NP_034591.1 Gene:Hoxb8 / 15416 MGIID:96189 Length:243 Species:Mus musculus


Alignment Length:228 Identity:84/228 - (36%)
Similarity:104/228 - (45%) Gaps:65/228 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   192 NSANSNNNNSQSL-------ASPQDLSTRDISPKL--SPSSVVESVARSLNKGVLGGSL------ 241
            ||..|.....:||       ...|||..|   |.:  .|||              |||.      
Mouse     7 NSLFSKYKTGESLRPNYYDCGFAQDLGGR---PTVVYGPSS--------------GGSFQHPSQI 54

  Fly   242 ------AAAAAAAGLNNNHSGSGVSGGPGNV--NVPMHSP---GGGDSD----------SESDSG 285
                  .::.:.|....|.......|.|||.  ..|:...   |..|.|          :.|..|
Mouse    55 QEFYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLG 119

  Fly   286 NEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLT 350
            .||..|:.|    .:|.|::|||:        ..|....:|.|.:|:|||||||||||.||.|||
Mouse   120 EEAEGSEQS----PSPTQLFPWMR--------PQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLT 172

  Fly   351 RRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 383
            |:||||::|||.|||||:||||||||||||||:
Mouse   173 RKRRIEVSHALGLTERQVKIWFQNRRMKWKKEN 205

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ScrNP_001368995.1 Homeobox 328..381 CDD:395001 42/52 (81%)
Hoxb8NP_034591.1 Antp-type hexapeptide 134..139 2/4 (50%)
Homeobox 150..203 CDD:395001 42/52 (81%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 203..243 2/3 (67%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X14
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
65.810

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