DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scr and Hoxa6

DIOPT Version :9

Sequence 1:	NP_001368995.1	Gene:	Scr / 40833	FlyBaseID:	FBgn0003339	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_034584.1	Gene:	Hoxa6 / 15403	MGIID:	96178	Length:	232	Species:	Mus musculus

Alignment Length:	133	Identity:	72/133 - (54%)
Similarity:	91/133 - (68%)	Gaps:	10/133 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 SGSGVSGGPGNVNVPMH-SPGGGDSDSESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTV 318
            ||:....|||:.   :| ||   :...:.|...:..:....|..:|....:||||:|::.....|
Mouse    91 SGNNKQRGPGDY---LHFSP---EQQYKPDGSVQGKALHEEGTDRKYTSPVYPWMQRMNSCAGAV 149

  Fly   319 -NANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKE 382
             .::|  :|.|.:||||||||||||||||||||||||||||:|||||||||||||||||||||||
Mouse   150 YGSHG--RRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 212

  Fly   383 HKM 385
            :|:
Mouse   213 NKL 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeobox	328..381	CDD:395001	49/52 (94%)
Hoxa6	NP_034584.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	88..126		9/40 (23%)
		Antp-type hexapeptide	135..140		3/4 (75%)
		Homeobox	158..210	CDD:278475	48/51 (94%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810