Protein Alignment Scr and Mnx1

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_064328.2
• Gene: Mnx1 / 15285
• MGIID: 109160
• Length: 404
• Species: Mus musculus
• Alignment Length: 568
• Identity: 132/568 - (23%)
• Similarity: 173/568 - (30%)
• Gaps: 268/568 - (47%)

  Fly    14 VNSLASCYPQQMNPQQNHPGAGNSSAGG--SGGGAGGSGGVVPSGGTNGG-------QGSAGAAT 69
            :::|.:..|.:....|:.|.|..:|...  ||.|.|||||    |||:.|       ..|...|.
Mouse     9 IDALLAVDPPRAASTQSAPLALVTSLATTVSGPGRGGSGG----GGTSSGASRSCSPASSEATAA 69

  Fly    70 PGANDYFPAAAAYTPNLYPNTPQAHYA------------NQAAYGGQGNPDMVDYTQLQPQRLLL 122
            ||  |...|.:...|.|.    .||.|            ...|.||.|.|
Mouse    70 PG--DRLRAESPSPPRLL----AAHCALLPKPGFLGAGGGGGAAGGPGTP--------------- 113

  Fly   123 QQQQQQQQQQHAH------AAAAVAAQQQQQLAQQQHPQQQQQQQQANISCKYANDPVTPGGSGG 181
                    ..|||      ||||.||.....||...||                     .|..||
Mouse   114 --------HHHAHPGAAAAAAAAAAAAAAGGLALGLHP---------------------GGAQGG 149

  Fly   182 GGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISPKLSPSSVVESVARSLNKGVLGG----SLA 242
            .|:..                                               :..|.|    |.:
Mouse   150 AGLPA-----------------------------------------------QAALYGHPVYSYS 167

  Fly   243 AAAAAAGLNNNH-----SGSGVSGG-PGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNP 301
            ||||||.|...|     |...|.|. |.:...|:                :.|:|..
Mouse   168 AAAAAAALAGQHPALSYSYPQVQGAHPAHPADPI----------------KLGASTF-------- 208

  Fly   302 PQIYPWMKRVHLG---------TSTVNAN--GETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRI 355
             |:..|::....|         :|...:|  |:.:|.||::|..|.||||.:|..|:||:|.:|.
Mouse   209 -QLDQWLRASTAGMILPKMPDFSSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRF 272

  Fly   356 EIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNIVPYHMGPYGHPYHQFDIHPSQFAHLSAXDA 420
            |:|.:|.|||.|:||||||||||||:..|
Mouse   273 EVATSLMLTETQVKIWFQNRRMKWKRSKK------------------------------------ 301

  Fly   421 WHFSGTGXRLNQLYQEPYQTAAAASAASGYQSQDGGPIGGGSVGVGGG--------AGGP--GSL 475
                                 |...||...:.|.|   |||..|.||.        .|.|  |..
Mouse   302 ---------------------AKEQAAQEAEKQKG---GGGGTGKGGSEEKTEEELMGPPVSGDK 342

  Fly   476 ANGG------------------------SNGSGPNSLFASAASSSQAP 499
            |:|.                        |||:|.::..:..:|...:|
Mouse   343 ASGRRLRDLRDSDPDEDEDDEEEDNFPYSNGAGAHAASSDCSSEDDSP 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	33/55 (60%)
Mnx1	NP_064328.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..80		18/49 (37%)
		Homeodomain	242..298	CDD:459649	33/55 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..404		23/152 (15%)