Protein Alignment Scr and Evx1

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_031992.1
• Gene: Evx1 / 14028
• MGIID: 95461
• Length: 416
• Species: Mus musculus
• Alignment Length: 406
• Identity: 106/406 - (26%)
• Similarity: 147/406 - (36%)
• Gaps: 135/406 - (33%)

  Fly   182 GGVSGSNNNNNSANSNNNNSQSLASPQDLSTRD--ISPKLSPSSVVESVARSLNKGVLGG----- 239
            ||..|:......:|.:...|..|..|.:.....  :||:..|.:       |..:|  ||
Mouse    13 GGQLGTLVGKRVSNLSEAVSSPLPEPPEKMVPHGCLSPRAGPPT-------SRERG--GGGQEEE 68

  Fly   240 ---SLAAAAAAAGLNNNHSGSGVSG-GP------------------------------------- 263
               .||.:||..|.....:|:.:.| ||
Mouse    69 PVDGLAGSAAGLGAEPRSAGAAMLGPGPPVPSADSLSGQGQPSSSDTESDFYEEIEVSCTPDCAT 133

  Fly   264 GNVNVPMHS--PGGGDSDSESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKR 326
            ||... .||  ||.....|...||:||..| |.|:|.....           ||...:|:.:.:|
Mouse   134 GNAEY-QHSKAPGSDALGSSPTSGSEAPKS-NGGSGGSGSQ-----------GTLACSASDQMRR 185

  Fly   327 QRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNIV 391
            .||::||.|...|||||:...|::|.||.|:|.||.|.|..||:||||||||.|::....:
Mouse   186 YRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMT---- 246

  Fly   392 PYHMGPYGHPYHQFDIHPSQFAHLSAXDAWHFSGTG-------XRLNQLYQEPYQTAAAASAASG 449
                  :.||     ..|:.:.::.:    |.:..|        .|...|..|. ...||||||.
Mouse   247 ------WPHP-----ADPAFYTYMMS----HAAAAGGLPYPFPSHLPLPYYSPV-GLGAASAASA 295

  Fly   450 YQSQDGGPI---------------------------------GGGSVGVGGGAGGPGS-LA--NG 478
            ..|...||:                                 |.|:......|.||.| ||  :|
Mouse   296 AASPFSGPLRPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLGASAAAAAAAGPCSCLACHSG 360

  Fly   479 GSNGSGPNSLFASAAS 494
            .:||..|.:..|:|||
Mouse   361 PANGLAPRAAAAAAAS 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	31/55 (56%)
Evx1	NP_031992.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..120		19/98 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	138..178		15/52 (29%)
		Homeodomain	184..240	CDD:459649	31/55 (56%)