Protein Alignment Scr and Dbx

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_061502118.1
• Gene: Dbx / 1276399
• VectorBaseID: AGAMI1_014192
• Length: 727
• Species: Anopheles gambiae
• Alignment Length: 659
• Identity: 143/659 - (21%)
• Similarity: 210/659 - (31%)
• Gaps: 241/659 - (36%)

  Fly     2 DPD-CFAMSSYQFVNSLASCYPQQMNPQQNHPGAGNSSAGGSGGGAGGSG--------------G 51
            ||| ..|:....||.:........:||.....|: ....||.|||...:|              .
Mosquito   146 DPDGVAALEPMDFVCAKCGHCQADLNPAAARDGS-PMVVGGDGGGDKRAGENNNNHSKEEEECDS 209

  Fly    52 VVPSGGTNGGQGSAGA-------------ATPGANDYFPAAAAYTPNLYPNTPQAHYANQAAYGG 103
            ||.......|:|....             ..||.......:         :.|...::..|..|.
Mosquito   210 VVTERRAGDGEGIGSEYEFRCEKCGFGEYVVPGKQTILKES---------SKPVLKFSVSAILGD 265

  Fly   104 QGNPDMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVAA------QQQQQLAQQQ---------- 152
            :.....|....:|||.|....||...||.|....|.:.|      ...|||....
Mosquito   266 RKECVKVRNEFIQPQHLWPYIQQNLIQQNHLANPAFLGAHPHHPHHPHQQLPPHHHHPHHHPHHH 330

  Fly   153 -----------HPQQQQQQQQANISCKYANDPV--------TPGGSGGGGVSGSNNNNNSANSNN 198
                       ||....||||.:::......|.        :..||||||  |.:::.:::||:|
Mosquito   331 HPHHHHHQPGTHPLSPHQQQQQHLTVGPNGSPTGGHVTNNSSSNGSGGGG--GPHHHLHNSNSSN 393

  Fly   199 NNSQSLASPQDLSTRDISPKLSPSSVVESVARSLNKGVLGGSLAAAAAA---AGLNNNHSGSGVS 260
            :.|:|.:.|.       ||:|...|...|..|. || ::...|.:....   ..||:.|..|.::
Mosquito   394 STSESGSLPN-------SPELQEPSATGSGPRD-NK-IIAKPLPSRPTPFLHHSLNHPHLHSLLA 449

  Fly   261 --------GGPGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTST 317
                    |||....:|   ||.|                            :||   .|
Mosquito   450 HCRNPYMPGGPQVFPLP---PGQG----------------------------FPW---AH----- 475

  Fly   318 VNANGETKR---QRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW 379
             :..|:.:|   :|..::..|...|||.|...:|:::..|.::|..|.|.:.|:|||||||||||
Mosquito   476 -STRGKPRRGMMRRAVFSDSQRKGLEKRFQLQKYISKPDRKKLAERLGLKDSQVKIWFQNRRMKW 539

  Fly   380 K--KEHKM-----------------------------ASMNIVPYHMGPYGHPYHQFDIHPSQFA 413
            :  ||.::                             .|::..|....|.|...|  |..|
Mosquito   540 RNSKERELLANGGSRDQTLPNKNNPNPDLSDARTDRQTSLSPPPPASPPQGSTPH--DGQP---- 598

  Fly   414 HLSAXDAWHFSGTGXRLNQLYQEPYQTAAAAS---AASGYQSQDGGP------------------ 457
                                  .|..|..:||   |.:.:|.|...|
Mosquito   599 ----------------------PPQPTTPSASPKPAPTAHQQQGAAPQPPPPPMLTFKSKFELLK 641

  Fly   458 ---IGGGSVG---------VGGGAGGPGS-LANGG--------SNGSGPNSLFASAASSSQAPDC 501
               :.||:..         |.||...||. ...||        :.|||.::  :||:|..|:...
Mosquito   642 PSAVAGGAGADFKFDFEDQVAGGNRPPGGHFPMGGFYPGATDPAVGSGRSN--SSASSELQSGAQ 704

  Fly   502 IKYPQEFXS 510
            ..|..|: |
Mosquito   705 AMYYDEYES 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	24/60 (40%)
Dbx	XP_061502118.1	None