Protein Alignment Scr and NK7.1

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_061504516.1
• Gene: NK7.1 / 1270404
• VectorBaseID: AGAMI1_010904
• Length: 600
• Species: Anopheles gambiae
• Alignment Length: 551
• Identity: 119/551 - (21%)
• Similarity: 196/551 - (35%)
• Gaps: 137/551 - (24%)

  Fly    67 AATPGANDYFPAAAAYTPNLYPNTPQ----AHY---------ANQAAYGGQGNPDMV---DYTQL 115
            |.:...:|.:.....:.|::|.|.|:    .|.         ...||.|.|.:...|   ::|:|
Mosquito    79 AHSKAPSDEWTKQTQWHPHVYANPPKQPPTPHSIMDILGWKGTGVAAVGTQNSHVPVREDNHTKL 143

  Fly   116 QPQRLLLQQQQQQQQQQHAHAA----AAVAAQQQQQLAQQQHP----QQQQQQQQANISCKYAN- 171
             |.|.|.....:::.:....:|    ..|..||||:...:...    .|.....:..|..|..|
Mosquito   144 -PYRSLFDAASKEECRDDVSSAYYRPTDVEEQQQQRSIVEDEDNITVDQDDDSDEDEIEEKRPNV 207

  Fly   172 ----DPVTPGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISP---KLSPSSVVESVA 229
                .|::|                     |:...:|...:..|:.|::|   :.:||....|:.
Mosquito   208 VERTRPMSP---------------------NDEPLNLCIVKHTSSADVTPPVRRKTPSLGRNSLE 251

  Fly   230 RSLNKGVL----GGSLAAAAAAAGLNNNHSGSGVSGG-----PGNVNVPMHSPGGGDSDSESDSG 285
            |...:.::    ....:..:::...:..|:.:.::..     |.:|..|.......|:||:....
Mosquito   252 RFHERKIMSEEDSTQESTRSSSVHYHQRHTPAHLTPAHHQQRPRSVVPPPALAHSSDADSDICMS 316

  Fly   286 NEAGSSQNSGNGKKNPPQIYPWMKRVHLGT----STVNANGET---------------------- 324
            |:..|:.:......|.......|....|.:    :.|.:||.|
Mosquito   317 NDDSSTADGHFSAVNDAVASATMTMSTLFSLPKPAGVPSNGVTAGAVLTEEETTTTSVPSHHRRK 381

  Fly   325 KRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMN 389
            |:.||::|..|..||||:|...:||:...|.|:|..|.:||.|:||||||||.||||: ..|...
Mosquito   382 KKARTTFTGRQIFELEKQFEVKKYLSSNERTEMAKLLNVTETQVKIWFQNRRTKWKKQ-DTAGSG 445

  Fly   390 IVPYHMGPYGHPYHQFDIHPSQFAHLSAXDAWHFSGTGXRLNQLYQEPYQTAAAASAASGYQSQD 454
            .||...|  ||..      ||..:..|..||.....:|...:.....|...||.||..|..:...
Mosquito   446 EVPASSG--GHAI------PSSPSPHSPKDATKGISSGSNSSSSSGRPLSNAAVASKLSATELPA 502

  Fly   455 GGP----------------------------IGGGSVGVGGG--------AGGPGSLANGGSNGS 483
            .||                            ....|..|..|        :.|.....:..|:.|
Mosquito   503 HGPAWVNELESGRPPPPPPAPTASQLGKSRAYAKASTAVRKGKQHPERHLSVGTSDRRSASSSSS 567

  Fly   484 G---PNSLFASAASSSQAPDCIKYPQEFXSQ 511
            |   .:|...|||:::..|..:::|.:..:|
Mosquito   568 GTAMSSSRSNSAAAAATTPTTVEHPGQQMAQ 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	29/55 (53%)
NK7.1	XP_061504516.1	None