Protein Alignment Scr and Alx3

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_031467.1
• Gene: Alx3 / 11694
• MGIID: 1277097
• Length: 343
• Species: Mus musculus
• Alignment Length: 454
• Identity: 96/454 - (21%)
• Similarity: 134/454 - (29%)
• Gaps: 155/454 - (34%)

  Fly    77 PAAAAYTPNLYPNTPQAHYANQAAYGGQGNPDMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVA 141
            |||..|..           |...|.|.||.||..                     .|.|.|....
Mouse    13 PAAGPYAA-----------AGDEAPGPQGTPDAA---------------------PHLHPAPPRG 45

  Fly   142 AQQQQQLAQQQHPQQQQQQQQANISCKYAND----PVTPGGSGGGGVSGSNNNNNSANSNNNNSQ 202
            .:..:..|  ..|.:....:.|....||..|    ||..||....|         ||.:....|:
Mouse    46 PRLSRFPA--CGPLEPYLPEPAKPPAKYLQDLGPGPVLNGGHFYEG---------SAEAEEKASK 99

  Fly   203 SLASPQ-DLSTRDISPKLSPSSVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGP--G 264
            :.:.|| .:..|. .|:..||:|                                 ..|.||  .
Mouse   100 AASFPQLPVDCRG-GPRDGPSNV---------------------------------QASPGPCLA 130

  Fly   265 NVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRT 329
            :::||: |||..||                                    ........:.:|.||
Mouse   131 SLSVPL-SPGLPDS------------------------------------MELAKTKSKKRRNRT 158

  Fly   330 SYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNIVPYH 394
            :::.:|..||||.|....|.....|.::|....|||.::::||||||.||:|..:...|.   ..
Mouse   159 TFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKMQ---EG 220

  Fly   395 MGPYGHPYH-----QFDIHPSQFAHLSAXDAWHFSGTGXRLNQLYQEPYQTAAAASAASGYQSQD 454
            ..|:...|.     :.|.||.....|     |...|:|.........|          .|..|..
Mouse   221 RNPFTTAYDISVLPRTDSHPQLQNSL-----WPSPGSGSPGGPCLMSP----------EGIPSPC 270

  Fly   455 GGPIGGGSVGVGGGAGGPGSLA--------NGGSNGSGPNSLFASAASSSQAPDCIKY---PQE 507
            ..|.......|.|..|.|.|.|        :|.....|.:|...|.....::|..:..   |:|
Mouse   271 MSPYSHSHGNVAGFMGVPASPAAHPGIYSIHGFPPALGGHSFEPSPDGDYKSPSLVSLRMKPKE 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	23/55 (42%)
Alx3	NP_031467.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..122		35/185 (19%)
		Homeodomain	154..210	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	309..343		5/26 (19%)