DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scr and Hoxa2

DIOPT Version :9

Sequence 1:	NP_001368995.1	Gene:	Scr / 40833	FlyBaseID:	FBgn0003339	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_036713.2	Gene:	Hoxa2 / 103690123	RGDID:	2813	Length:	372	Species:	Rattus norvegicus

Alignment Length:	148	Identity:	58/148 - (39%)
Similarity:	72/148 - (48%)	Gaps:	29/148 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   263 PGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNP-----PQIYPWMKRVHLGTSTV---- 318
            |....:|..:||.....| :.:|....||.....|...|     |..|||||.......|.
  Rat    51 PFEQTIPSLNPGSHPRQS-AGAGGRPKSSPAGSRGSPVPARALQPPEYPWMKEKKAAKKTALPPA 114

  Fly   319 -------------------NANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLT 364
                               .:.|.::|.||:||..|.||||||||||:||.|.||:|||..|.||
  Rat   115 AASTGPACLGHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLT 179

  Fly   365 ERQIKIWFQNRRMKWKKE 382
            |||:|:||||||||.|::
  Rat   180 ERQVKVWFQNRRMKHKRQ 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeobox	328..381	CDD:395001	38/52 (73%)
Hoxa2	NP_036713.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	42..96		11/45 (24%)
		Antp-type hexapeptide	96..101		3/4 (75%)
		Homeobox	143..196	CDD:395001	38/52 (73%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	194..225		1/4 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910