DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scr and hoxc6

DIOPT Version :9

Sequence 1:	NP_001368995.1	Gene:	Scr / 40833	FlyBaseID:	FBgn0003339	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	XP_004911991.1	Gene:	hoxc6 / 101733663	XenbaseID:	XB-GENE-478131	Length:	242	Species:	Xenopus tropicalis

Alignment Length:	231	Identity:	92/231 - (39%)
Similarity:	118/231 - (51%)	Gaps:	55/231 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 NSANSNNNNSQSLASPQDLSTRDISPKLSPSSVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSG 256
            ||..:|.:.|..|||.|     ::.|.::.:|......|         ..:...||...|..:|.
Frog     2 NSYFTNPSLSCHLASGQ-----EVLPNVALNSTAYDPVR---------HFSTYGAAVAQNRIYSS 52

  Fly   257 S----------GVSGGP---GN----------VNVPMHSPGGGDSDSESDSGNEAGSSQNSGNG- 297
            .          |.|.||   |:          .:...:|.|   .:::|....:..|.|:.|||
Frog    53 PFYTPQDNVVFGSSRGPYEYGSNAFYQDKDMLTSCRQNSMG---HNTQSSLAQDFSSEQSRGNGQ 114

  Fly   298 -KKNPPQIYPWMKRVH----------LGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTR 351
             :|...||||||:|::          ||   |....:.:|.|..|:|||||||||||||||||||
Frog   115 EQKGSIQIYPWMQRMNSHSVCLVSDSLG---VGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTR 176

  Fly   352 RRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMAS 387
            |||||||:|||||||||||||||||||||||..:.|
Frog   177 RRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTS 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeobox	328..381	CDD:395001	48/52 (92%)
hoxc6	XP_004911991.1	Homeobox	153..205	CDD:278475	47/51 (92%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000