Protein Alignment Scr and Hoxa10

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001389216.1
• Gene: Hoxa10 / 100911668
• RGDID: 9410935
• Length: 413
• Species: Rattus norvegicus
• Alignment Length: 455
• Identity: 128/455 - (28%)
• Similarity: 165/455 - (36%)
• Gaps: 157/455 - (34%)

  Fly     7 AMSSYQFVNSLASCYPQQMNPQQNHPGAGNSSAGGSGGGAGGSGGVV------------------ 53
            |.:|: .|:||.|       ..:...|.|..||||.|||....|||.
  Rat    25 AANSF-LVDSLIS-------SGRGEAGGGGGSAGGGGGGYYAHGGVYLPPASDLPYGLQSCGLFP 81

  Fly    54 -----------PSGGTNGGQGSAGAATPGANDYFPAAAAYTPNLYPNTPQAHYANQAAYGGQGNP 107
                       |.||..||.|..|   |||:.|.||..    :|:.:.|::.....        |
  Rat    82 ALGNKRNEAPSPGGGGGGGGGGLG---PGAHGYAPAPL----DLWLDAPRSCRMEP--------P 131

  Fly   108 DMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVAAQQQQQLAQQQHPQQQQQQQQANISCKYAND 172
            |.....|.||                          ||||......||..|...||. ||.:|.:
  Rat   132 DGPPPPQPQP--------------------------QQQQQPPPPPPQPPQPPPQAT-SCSFAQN 169

  Fly   173 ----------------------------PVTP-------GGSGGGGVSG----SNNNNNSANSNN 198
                                        |..|       |.|.|..|.|    |.....:....:
  Rat   170 IKEESSYCLYDSADKCPKGSAAADLAPFPRGPPPDGCALGASSGVPVPGYFRLSQAYGTAKGFGS 234

  Fly   199 NNSQSLASPQDLST--RDISPKLSPSSVVESVARSLNK-GVLGGSLAAAAAAAGLNNNHSGSGVS 260
            ..:|.||||.....  |...|   ||::....|.:..| .||..:.......||
  Rat   235 GGTQQLASPFPAQPPGRGFDP---PSALASGSAEAAGKERVLDSTPPPTLVCAG----------- 285

  Fly   261 GGPGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVN--ANGE 323
            ||....:...|:         |.|..|..|...|.|.|.:|       ::..||.|...  ||..
  Rat   286 GGSSQADEEAHA---------SSSAAEELSPAPSENSKASP-------EKDSLGNSKSENAANWL 334

  Fly   324 T----KRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 384
            |    :::|..||::|||||||||.||.||||.||:||:.::.||:||:||||||||||.||.::
  Rat   335 TAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNR 399

  Fly   385  384
              Rat   400  399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	36/55 (65%)
Hoxa10	NP_001389216.1	PRK07764	<188..331	CDD:236090	37/172 (22%)
		Homeodomain	340..396	CDD:459649	36/55 (65%)