Protein Alignment Scr and en2

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_002932525.1
• Gene: en2 / 100498251
• XenbaseID: XB-GENE-853108
• Length: 266
• Species: Xenopus tropicalis
• Alignment Length: 258
• Identity: 74/258 - (28%)
• Similarity: 101/258 - (39%)
• Gaps: 59/258 - (22%)

  Fly   195 NSNNNNSQSLASPQDLSTRDISPKLSPSS----------VVESVAR--------------SLNKG 235
            |..||.........|.|.|.|..:..|.:          .::::.|              .|..|
 Frog     4 NEQNNREVEPQESGDESNRGILHQAPPGNHQPHHRITNFFIDNILRPEFGRRKEGISHQDELFSG 68

  Fly   236 VLGGSLAAAAAAAGLNNNHSGSGVS-----GGPGNVNVPMH----SPG-GGDSDSESDSGNEAGS 290
            ...|:|:.|.:|....|...|:|.|     .|....::.|.    |.| .||....|||.:...|
 Frog    69 RDSGALSGAESAHHRANATEGAGGSKAITLTGDKKSDIAMEESLKSRGHNGDHSLSSDSDSSQAS 133

  Fly   291 SQNSGNGKKNPPQIYP-WM--------------KRVHLGTSTVNANGETKRQRTSYTRYQTLELE 340
            |:.|     ..|.::| |:              .|.....:|.....|.||.||::|..|...|:
 Frog   134 SKTS-----QQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKTTTTVTKEDKRPRTAFTADQLQRLK 193

  Fly   341 KEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNIVPYHM---GPYGH 400
            .||..|||||.:||..:|..|.|.|.||||||||:|.|.||  ...:.|.:..|:   |.|.|
 Frog   194 AEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKK--ATGNKNSLALHLMAQGLYNH 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	30/55 (55%)
en2	XP_002932525.1	Homeodomain	178..234	CDD:459649	30/55 (55%)
		Engrail_1_C_sig	235..265	CDD:431338	5/20 (25%)