Protein Alignment Scr and pdx1

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_002934065.1
• Gene: pdx1 / 100490648
• XenbaseID: XB-GENE-483331
• Length: 271
• Species: Xenopus tropicalis
• Alignment Length: 284
• Identity: 83/284 - (29%)
• Similarity: 115/284 - (40%)
• Gaps: 99/284 - (34%)

  Fly   114 QLQPQRLLLQQ----QQQQQQQQHAHAAAAVAAQQQQQLAQQQHPQQQQQQQQANISCKYANDPV 174
            |..||..|.::    |:.|.|..:....|.:...:|||.|                   |:|..|
 Frog     6 QYYPQAPLYKEPCAFQRSQAQDYNPSPPACLYMGRQQQAA-------------------YSNPLV 51

  Fly   175 T--PGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISPKLSPSSVVESVARSLNKGVL 237
            .  ||                            ||.|:|..:: |.:|...:|..:....:
 Frog    52 ALDPG----------------------------SPPDISPYEV-PPISEEPIVPHLHHHHH---- 83

  Fly   238 GGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKKNPP 302
                         :::|...|:......:..|        .|:||.:..|           :|..
 Frog    84 -------------HHHHHHPGIPHPHQQMPFP--------DDTESATLEE-----------RNRT 116

  Fly   303 QI-YPWMK--RVH------LGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIA 358
            .: :||||  :.|      .|.|.:....|.||.||:|||.|.|||||||.||:|::|.||:|:|
 Frog   117 LLPFPWMKSTKSHTWKGQWTGGSYIMEQEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELA 181

  Fly   359 HALCLTERQIKIWFQNRRMKWKKE 382
            ..|.||||.|||||||||||||||
 Frog   182 VMLNLTERHIKIWFQNRRMKWKKE 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	40/55 (73%)
pdx1	XP_002934065.1	Homeodomain	148..204	CDD:459649	40/55 (73%)