Protein Alignment Scr and nkx2-3

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_002937234.1
• Gene: nkx2-3 / 100486189
• XenbaseID: XB-GENE-852996
• Length: 328
• Species: Xenopus tropicalis
• Alignment Length: 299
• Identity: 72/299 - (24%)
• Similarity: 96/299 - (32%)
• Gaps: 91/299 - (30%)

  Fly   107 PDMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVAAQQQQQLAQQQHPQQQQQQQQANISCKYAN 171
            |..|..|....:.:|..:||.|....|..     ..|||...|...||.|.........||..|.
 Frog     4 PSPVTSTPFSVKDILNLEQQGQPPIAHPQ-----HLQQQCSRAHPAHPAQDLDSDFQQASCMLAA 63

  Fly   172 DP--VTPGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISPKLSPSSVVESVARSLNK 234
            ..  |..||                                  .|..|.||
 Frog    64 GERCVYAGG----------------------------------EDKLPFLS-------------- 80

  Fly   235 GVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEAG------SSQN 293
                        |.|....|...|:|  |... |.:..|...| :.|.||..|.|      :...
 Frog    81 ------------AMGAAEPHGDVGLS--PDRY-VALRDPKEED-EEEEDSLREGGNKSCFLNKSP 129

  Fly   294 SGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIA 358
            .|.||...|.......|              ::.|..:::.|..|||:.|...|||:...|..:|
 Frog   130 DGEGKLEDPDRPKQRSR--------------RKPRVLFSQAQVFELERRFKQQRYLSAPEREHLA 180

  Fly   359 HALCLTERQIKIWFQNRRMKWKKEHKMASMNIVPYHMGP 397
            ::|.||..|:||||||||.|.|::.:..|:.:..:|..|
 Frog   181 NSLKLTSTQVKIWFQNRRYKCKRQRQDKSLEMGTHHPPP 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	24/55 (44%)
nkx2-3	XP_002937234.1	Homeodomain	147..203	CDD:459649	24/55 (44%)