Protein Alignment Scr and nkx3-3

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_002937227.1
• Gene: nkx3-3 / 100485176
• XenbaseID: XB-GENE-479908
• Length: 241
• Species: Xenopus tropicalis
• Alignment Length: 265
• Identity: 68/265 - (25%)
• Similarity: 106/265 - (40%)
• Gaps: 75/265 - (28%)

  Fly   210 LSTRDISPKLSPSSVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPG-----NVNVP 269
            :|...:|| |:..|:.:.:||:...            :.|.|..:.|:|.:.|..     ..:.|
 Frog     1 MSLTGVSP-LTSFSIQDILARTCRD------------SNGGNEGNGGNGDNTGKAKRTDEKSSTP 52

  Fly   270 MHSPGG-GDSD---------------SESDSGNEAGS--SQNSGNGKKNPPQIYPWMKRVHLGTS 316
            .|||.. |.:|               :::|||.|..:  .:.:..|....|.     ....||.|
 Frog    53 PHSPSAEGHNDWPQADNPPLTPEKEKTDTDSGTEDSTWEPEAASTGAYTDPS-----SGDLLGDS 112

  Fly   317 TVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 381
            ..::.   ||.|.:::..|..|||:.|...|||:...|.::|.||.|||.|:||||||||.|.|:
 Frog   113 PKSSK---KRSRAAFSHAQVYELERRFSLQRYLSGPERADLAAALKLTETQVKIWFQNRRYKTKR 174

  Fly   382 E---------------HKMASMNIVPYHMGPYG-----HP-----YHQFDIHPSQFAHLSAXDAW 421
            :               .|:|...:|......|.     :|     ||.:..:|    ::.. .||
 Frog   175 KLIATQTAPKSSLAPARKVAVRVLVKDDQRQYCPEDILNPSLLSLYHAYQYYP----YMYCLPAW 235

  Fly   422 --HFS 424
              |.|
 Frog   236 VPHLS 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	28/55 (51%)
nkx3-3	XP_002937227.1	Homeodomain	118..174	CDD:459649	28/55 (51%)