Protein Alignment Scr and Hoxb2

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001386664.1
• Gene: Hoxb2 / 100361765
• RGDID: 2319509
• Length: 355
• Species: Rattus norvegicus
• Alignment Length: 316
• Identity: 92/316 - (29%)
• Similarity: 119/316 - (37%)
• Gaps: 112/316 - (35%)

  Fly   289 GSSQNSGNGK--KNPPQI--------YPWMKRVHL-------------GTSTVNANG-------- 322
            ||.:.:|:|.  :.||.:        :||||....             ..|:|.|:|
  Rat    68 GSQKPAGDGPALRPPPPLPVAPPAPEFPWMKEKKSAKKPSQSAATPSPAASSVRASGVGSPSDGP 132

  Fly   323 --------ETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW 379
                    .::|.||:||..|.||||||||||:||.|.||:|||..|.|||||:|:||||||||
  Rat   133 GLPESGGSGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMK- 196

  Fly   380 KKEHKMASMNIVPYHMGPYGHP---YHQFDI-HPSQFAHLSAXDAWHFSGTGXRLNQLYQEPYQT 440
               ||..:.:..|    |.|.|   ..|.|. .|::...:|..|.     ...||.:....|
  Rat   197 ---HKRQTQHREP----PDGEPGGLSAQDDAGEPAEEPTVSPGDV-----ASHRLREACFLP--- 246

  Fly   441 AAAASAASGYQSQDGGPIGGGSVGVGGGAGGPGSLANGGSNGSGPNSLFASAASSSQAPDCIKYP 505
               |.||.|.:                  |.|..|.        |.:...|..:||  |.|
  Rat   247 ---AEAAQGPR------------------GAPPPLP--------PATALESVGASS--PGC---- 276

  Fly   506 QEFXSQVIIRQQHQQQQDNSMDRNQER-------DLKLLLETDCEP-----DPELQ 549
                  .::|....|.:....|...||       ||.......|.|     .|.||
  Rat   277 ------TMLRAGGLQSEPLPEDACPERQDSPFLPDLNFFAADSCLPMSGGLSPSLQ 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	39/55 (71%)
Hoxb2	NP_001386664.1	Homeodomain	143..199	CDD:459649	40/59 (68%)