Protein Alignment Scr and hoxa3

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001120901.1
• Gene: hoxa3 / 100151729
• XenbaseID: XB-GENE-482267
• Length: 406
• Species: Xenopus tropicalis
• Alignment Length: 463
• Identity: 118/463 - (25%)
• Similarity: 158/463 - (34%)
• Gaps: 171/463 - (36%)

  Fly    94 HYANQAAYGGQGNPDMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVAAQQQQQLAQQQHPQQQQ 158
            :|.:.|.|||........:|            ....|||:..:::.:..:..:.....|.|....
 Frog     6 YYDSSAIYGGYPYQGANGFT------------YNASQQQYPPSSSLLETEYHRPACSLQSPGSAV 58

  Fly   159 QQQQANISCKYANDPVTPGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISPKLSPSS 223
            ...:|                         |:.|.:.....||||..:|       :.|:..|:.
 Frog    59 PHHKA-------------------------NDINESCMRTINSQSNQAP-------VIPEQQPTP 91

  Fly   224 VVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEA 288
                                                .|.|.:|:.|            ..:.|.|
 Frog    92 ------------------------------------QGPPPSVSPP------------QTTSNAA 108

  Fly   289 GSSQNSGNGKKNP---PQIYPWMKRVHLGTSTVNA----NGE-------------TKRQRTSYTR 333
            .:|.|......:|   .||:||||.....|....|    :||             :||.||:||.
 Frog   109 TASSNKATSITSPTMSKQIFPWMKESRQNTKQQKAGSSSSGESCAGDKSPPGQSSSKRARTAYTS 173

  Fly   334 YQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASM---------- 388
            .|.:||||||||||||.|.||:|:|:.|.||||||||||||||||:||:.|..||
 Frog   174 AQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKSMMTSSGGQSPC 238

  Fly   389 --------------------NIVPY-----------HMGPYGHPYHQFDIHPSQFAHLSAXDAWH 422
                                |.|||           |...||.|......|.|...|..     .
 Frog   239 RSPVPTPSVGGYLNSMHSLVNSVPYEPQSPPAFNKHHPSAYGVPAPYPSPHNSCPPHQK-----R 298

  Fly   423 FSGTGXRLNQLYQEPYQTAAAASAASGYQSQDGGP--IGGGSVGVGGGAG----GPGSLANGGSN 481
            :|||.....:....|.|   .:|.|.|.....|.|  :||..|.....:|    |...|::..||
 Frog   299 YSGTAAVTPEYEPHPLQ---QSSGAYGNPHVQGSPVYVGGNYVETMTNSGPSMFGLSHLSHSSSN 360

  Fly   482 ----GSGP 485
                |:||
 Frog   361 MDYSGAGP 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	41/55 (75%)
hoxa3	NP_001120901.1	Homeodomain	165..221	CDD:459649	41/55 (75%)
		DUF4074	343..404	CDD:463833	8/26 (31%)