Protein Alignment Scr and hoxd3

DIOPT Version :10

• Sequence 1: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_002935734.1
• Gene: hoxd3 / 100038058
• XenbaseID: XB-GENE-478462
• Length: 415
• Species: Xenopus tropicalis
• Alignment Length: 476
• Identity: 125/476 - (26%)
• Similarity: 178/476 - (37%)
• Gaps: 168/476 - (35%)

  Fly    93 AHYANQAAYGGQGNPDMVDYTQLQPQRLLLQQQQQQQQQQHAHAAAAVAAQQQQQLAQQQHPQQQ 157
            |:|.|...:||        ||..:|             :.:::..           :|||:||..
 Frog    21 AYYENSGLFGG--------YTYAKP-------------ESYSYGP-----------SQQQYPQSS 53

  Fly   158 QQQQQANISCKYANDPVTPGGSGGGGVSGSNNNNNSANSNNNNSQSLASPQDLSTRDISPKLSPS 222
            ......:.:|......:.........:|||.....| :.|:|.:.|:::.|..     :|.|.||
 Frog    54 LDSDYPSTACSIQPAAIRAPNHKANDISGSCMRTTS-SQNSNQAPSISNQQHQ-----APSLPPS 112

  Fly   223 SVVESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNE 287
            |                                             |.|  |...:..:|.|.|.
 Frog   113 S---------------------------------------------PSH--GNSSAQKKSKSSNS 130

  Fly   288 AGSSQNSGNGKKNPPQIYPWM-------KRVHLGTSTVNANGE-----------TKRQRTSYTRY 334
            :||||.:.:     .||:|||       |:.:..:|:....||           :||.||:||..
 Frog   131 SGSSQATLS-----KQIFPWMKESRQNAKQKNTSSSSSTPPGENCEEKSPTGPSSKRVRTAYTSA 190

  Fly   335 QTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNIVPYHMGPYG 399
            |.:||||||||||||.|.||:|:|:.|.||||||||||||||||:||:.|...:...|....|
 Frog   191 QLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGIMHSPAGQSP-- 253

  Fly   400 HPYHQFDIHPSQFAHLSAXDAWHFSGTGXRLNQL-YQEPYQTAAAASAASGY------------- 450
                  |..|:    ||. :...:|... .:|.| |..|..|:.|.|..:.|
 Frog   254 ------DRSPT----LSGSNHVGYSSQLPTVNSLSYDAPSPTSFAKSQQNMYGLAAYTAPLSSCL 308

  Fly   451 ----------------QSQDG--GP-IGGGSVGVGGG------AGGPGSLANGGSNGSGPNSLFA 490
                            |...|  .| :.|..|.|||.      |.||  :.|.| :.|.|:|...
 Frog   309 PQQKRYPGAEYEHHTMQGNSGFANPNLQGSPVYVGGNFVDSMPASGP--MFNVG-HLSHPSSASV 370

  Fly   491 SAASSSQAP------DCIKYP 505
            ..:.::|.|      .|..:|
 Frog   371 DYSCAAQIPGNHHHGPCDPHP 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	41/55 (75%)
hoxd3	XP_002935734.1	Homeodomain	181..237	CDD:459649	41/55 (75%)
		DUF4074	352..413	CDD:463833	12/43 (28%)