Protein Alignment Dfd and Nkx6-1

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_113925.1
• Gene: Nkx6-1 / 65193
• RGDID: 69318
• Length: 365
• Species: Rattus norvegicus
• Alignment Length: 381
• Identity: 77/381 - (20%)
• Similarity: 129/381 - (33%)
• Gaps: 134/381 - (35%)

  Fly   123 SAGGYSSNYANATPPSHPHS-----HPHAHPHQSLGYYVHHAPEFISAGAVH------SDPTNGY 176
            |:...||:.::.:||...|:     .|.|....|||    ..|:.:||...|      |.|:...
  Rat    49 SSSSSSSSSSSPSPPLGAHNPGGLKPPAAGGLSSLG----SPPQQLSAATPHGINDILSRPSMPV 109

  Fly   177 GPAANVPNTSNGGGGGGSGAVLGGGAVGGSANGYYGGYGGGYGTANGSVGSTHSQGHSPHSQMMD 241
            ...|.:|:.|..|....|.:  ...|...||            .|..:..:..:...||...:..
  Rat   110 ASGAALPSASPSGSSSSSSS--SASATSASA------------AAAAAAAAAAAAASSPAGLLAG 160

  Fly   242 LPLQCSSTEPP-------TNTALGLQELGLKLEKRIEEAVPAGQQLQELGM---------RLRCD 290
            ||...|.:.||       :.:|..:..:| :..|.:.| :|....:...|:         ||.|
  Rat   161 LPRFSSLSPPPPPPGLYFSPSAAAVAAVG-RYPKPLAE-LPGRTPIFWPGVMQSPPWRDARLAC- 222

  Fly   291 DMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGV 355
                    ...:..::||:                            ||:|
  Rat   223 --------TPHQGSILLDK----------------------------DGKR-------------- 237

  Fly   356 ANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMK 420
                       |..|..::..||..|||.|...:||....|..:|::|.::|.|:|:||||||.|
  Rat   238 -----------KHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTK 291

  Fly   421 WKKDNKLPNTKNVRKKTVDANGNPTPVAKKPTKRAASKKQQQAQQQQQSQQQQTQQ 476
            |:|                         |...:.|.:||:|.::.::.....:.::
  Rat   292 WRK-------------------------KHAAEMATAKKKQDSETERLKGTSENEE 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	22/51 (43%)
Nkx6-1	NP_113925.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..136		23/92 (25%)
		Repressor domain. /evidence=ECO:0000250	102..269		43/244 (18%)
		Homeobox	240..294	CDD:395001	23/53 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	295..365		5/28 (18%)
		Involved in DNA-binding. /evidence=ECO:0000250	307..365		1/16 (6%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910