Protein Alignment Dfd and Vax1

DIOPT Version :10

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_072158.1
• Gene: Vax1 / 64571
• RGDID: 621132
• Length: 336
• Species: Rattus norvegicus
• Alignment Length: 236
• Identity: 58/236 - (24%)
• Similarity: 92/236 - (38%)
• Gaps: 65/236 - (27%)

  Fly   316 SNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQ-----PGME---PKRQRTA 372
            |.|.:....:|.:|.|              :.::|.|.. |.||.:     .|::   |||.||:
  Rat    57 SEDCNKSKSNSSADPD--------------YCRRILVRD-AKGSIREIILPKGLDLDRPKRTRTS 106

  Fly   373 YTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKT 437
            :|..|:..||.||...:|:..|.|.|:|..|.|||.|:|:||||||.|.|||
  Rat   107 FTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKD------------- 158

  Fly   438 VDANGNPTPVAKKPTKRAASKKQQQAQQQQQSQQQ-------QTQQTPVMNECIRSDSLESI--- 492
               .|..:.:....::.||:....:..:|.:....       ....|..:...:|..||.::
  Rat   159 ---QGKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAG 220

  Fly   493 ----------------GDVSSSLGNPPYIPAAPETTSSYPG 517
                            |...::..:||.:..||....:.||
  Rat   221 AAAGSAAAAAAAATAPGPAGAASQHPPAVGGAPGPGPAGPG 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeodomain	367..423	CDD:459649	28/55 (51%)
Vax1	NP_072158.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..39
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	50..69		3/11 (27%)
		vax upstream domain	72..99		7/41 (17%)
		homeobox	100..159		32/74 (43%)
		Homeodomain	101..157	CDD:459649	28/55 (51%)
		vax downstream domain	178..189		1/10 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	236..267		7/26 (27%)
		vax terminal domain	315..323