DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and hmx3a

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_571709.2	Gene:	hmx3a / 60310	ZFINID:	ZDB-GENE-001020-1	Length:	297	Species:	Danio rerio

Alignment Length:	234	Identity:	62/234 - (26%)
Similarity:	100/234 - (42%)	Gaps:	61/234 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   293 GSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAE--TTDGERI--IYPWMKKIHVA 353
            |::.|    ...|:|...||   :.|::||  :...||.::.|  |.||::.  |..|.|.
Zfish   108 GTDRD----SPELVLKSDPD---AKDDEDD--NKSGDEIVLEESDTEDGKKEGGIDDWKKS---- 159

  Fly   354 GVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRR 418
              .:|:.:.....|:.||.::|.|:.:||..|...|||:...|..:|.:|.|:|.|:||||||||
Zfish   160 --DDGADKKPCRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRR 222

  Fly   419 MKWKKDNKLPNTKNVRKKTVDANGNPTPVAKKPTKRAASKKQQQAQQQQQSQQQQTQQTPVM-NE 482
            .|||:                             :.||   :.:|.....:..|:..:.|:: :|
Zfish   223 NKWKR-----------------------------QLAA---ELEAANLSHAAAQRIVRVPILYHE 255

  Fly   483 CIRSDSLESIGDVSSSLGNPPYIPAAPETTSSYPGSQQH 521
            ...|:|..:.|:|..|         .|..|..:|....|
Zfish   256 NSASESTNTAGNVPVS---------QPLLTFPHPVYYSH 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	25/51 (49%)
hmx3a	NP_571709.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	24..43
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	96..172		19/78 (24%)
		Homeobox	173..226	CDD:278475	25/52 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910