DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and hoxc1a

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_571606.1	Gene:	hoxc1a / 58046	ZFINID:	ZDB-GENE-000822-2	Length:	302	Species:	Danio rerio

Alignment Length:	324	Identity:	87/324 - (26%)
Similarity:	127/324 - (39%)	Gaps:	107/324 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 LPHHHSNSAISGHHQASAGGYSSNYANATPPSHPHS---HPHAHPHQSLGYYVHHAPEFISAGAV 168
            |.:|.:|...:.....|........||:|.|..|.:   :...||::.      ..|.|.|. ..
Zfish    49 LQYHFTNLCATATGACSKPCEDPGRANSTRPPFPQNQDFYRPVHPNRP------QVPSFQSC-RE 106

  Fly   169 HSDPTNGYGPAANVPNTSNGGGGGGSGAVLGGGAVGGSANGYYGGYGGGYGTAN---GSVGSTHS 230
            ......|:.|:::...|                                :.:|:   |.|.:|.:
Zfish   107 QGLSRKGFSPSSDTFRT--------------------------------FSSAHCELGPVNNTQT 139

  Fly   231 QGHSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSE 295
            :     .:..|.|::.|:.| ..||..|..       ..:.|.:.:|:..:  .||:|
Zfish   140 E-----VRTYDGPVRHSAVE-DDNTGHGAL-------NTLNETLHSGKTFE--WMRVR------- 182

  Fly   296 NDDMSEEDRLMLDRSPD-ELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGS 359
             .:.|...::.|.:..| ||.:|..      .|||||    |:.|                  ||
Zfish   183 -RNQSRAAKIQLGKCSDRELKTNHG------RDSDED----TSSG------------------GS 218

  Fly   360 YQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKK 423
                      ||.:|..|:.|||||||:|:||||.||||||:.|.|||.|:||||||||||.||
Zfish   219 ----------RTNFTTKQLTELEKEFHFNKYLTRARRIEIANPLQLSETQVKIWFQNRRMKQKK 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	37/51 (73%)
hoxc1a	NP_571606.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	198..224		15/63 (24%)
hoxc1a	NP_571606.1	Homeobox	218..271	CDD:278475	38/62 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810