Protein Alignment Dfd and AgaP_AGAP004646

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: XP_001688962.1
• Gene: AgaP_AGAP004646 / 5667644
• VectorBaseID: AGAP004646
• Length: 577
• Species: Anopheles gambiae
• Alignment Length: 690
• Identity: 296/690 - (42%)
• Similarity: 356/690 - (51%)
• Gaps: 217/690 - (31%)

  Fly     1 MSSFLMGYPHAPHHVQSPMSMGNGLDPKFPPLADDYHHYNGHY---------------------- 43
            ||||||||||  ||:|   |||..::||||| ::||.:::..|
Mosquito     1 MSSFLMGYPH--HHIQ---SMGINIEPKFPP-SEDYANFHSGYGVGNNVTQAGTQDYLHHIQSES 59

  Fly    44 ---------------SMTASTGHMSGA--------VGGGAGVGSVGGGGA---GGMTGHPHSMHP 82
                           .:|...||:|||        .|||.|||..|||||   ||.....::.:.
Mosquito    60 LHHAGAMSIGVPSGNGLTGGNGHVSGAGSNAEGEERGGGGGVGGGGGGGAEGGGGGVSAAYNDYS 124

  Fly    83 ADMVSDYMAHHHNPHSHSHSHTHSLPHHHSNSAISGHHQASAGGYSSNYANATPPSHPHSHPHAH 147
            :.||..|   :|:||.|.|.|     |||                           |||:|   |
Mosquito   125 SSMVGHY---YHHPHHHHHHH-----HHH---------------------------HPHAH---H 151

  Fly   148 PHQSLGYY----------------VHHAPEFISAGAVHSDPTNGYGPAANVPNTSNGGGGGGSGA 196
            |..: ||.                :...|..:|..|.:|..:|......|:
Mosquito   152 PSHN-GYMSPVQMQSTSSGLIAPAITTLPPSVSTAASNSSVSNQNSFPTNI-------------- 201

  Fly   197 VLGGGAVGGSANGYYGGYGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQE 261
                      .:|||.||              :|.....|:.:||.||||..|| .|||||||||
Mosquito   202 ----------TSGYYNGY--------------YSASTEGHTSIMDTPLQCVGTE-VTNTALGLQE 241

  Fly   262 LGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDND-DDL-G 324
            ||:||::|||||.|.|||||||||||||||..|:.|:..:|:|||||:|||||.|||.| ||| .
Mosquito   242 LGMKLDRRIEEAAPTGQQLQELGMRLRCDDASSDQDEFLDEERLMLDQSPDELDSNDGDIDDLES 306

  Fly   325 DSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNR 389
            |:|..||:|..|:||||||||||||||||||||||:|||||||||||||||||||||||||||||
Mosquito   307 DNDLGEDVMHATSDGERIIYPWMKKIHVAGVANGSFQPGMEPKRQRTAYTRHQILELEKEFHYNR 371

  Fly   390 YLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVD-----ANGNPTPVAK 449
            |||||||||||||||||||||||||||||||||||||||||||||||..|     |:|:......
Mosquito   372 YLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKNGDQSKSNASGSTGQSGV 436

  Fly   450 KPTKRAASKKQQQAQQQQQSQQQQTQQTPVMNECIRSDSLESIGDVSSSLGNPPYIPAAPETTSS 514
            ...::.:.|........:..|||||.|    |||:|:|||||:.||..::           ||.:
Mosquito   437 INNQKKSRKVSSTTLSTKSKQQQQTLQ----NECLRTDSLESMADVHGTI-----------TTIN 486

  Fly   515 YPGSQQHLSNNNNN----GSGNNNNNNNNNNSNL--------------------------NNNNN 549
            ...||...|::.||    .:|.||::|...|.:|                          |||||
Mosquito   487 TSSSQYMSSSDVNNTLPMANGTNNSSNTIRNEHLSQHQQLPHNQQQHHQLRQSQLSNQSSNNNNN 551

  Fly   550 NNQMGHTNLHGHLQQQQSDLMTNLQLH---IKQDYDLTAL 586
            :|..|:              |.|:|.|   ||.|||||||
Mosquito   552 SNATGN--------------MNNVQQHSVLIKNDYDLTAL 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	51/51 (100%)
AgaP_AGAP004646	XP_001688962.1	Homeobox	352..404	CDD:278475	51/51 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	259	1.000	Domainoid score	I4622
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	454	1.000	Inparanoid score	I3439
OMA	1	1.010	-	-		QHG25934
OrthoDB	1	1.010	-	-		D858478at2759
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	1	1.000	-	-		oto106242
Panther	1	1.100	-	-	LDO	PTHR45771
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X15331
TreeFam	1	0.960	-	-
	12	11.940