DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and nkx3-1

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_001373254.1	Gene:	nkx3-1 / 555375	ZFINID:	ZDB-GENE-081104-238	Length:	185	Species:	Danio rerio

Alignment Length:	138	Identity:	47/138 - (34%)
Similarity:	67/138 - (48%)	Gaps:	18/138 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   292 MGSENDDMSE---EDRLML---DRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKI 350
            |.:.|..::.   ||.|.|   .:..|...:..:.||..|..:|......|::|        |.:
Zfish     1 MATSNKQLTSFFIEDILSLKEDKKDEDSCNAESDRDDSTDRQTDSADTCRTSEG--------KTV 57

  Fly   351 HVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQ 415
            ....:..|    |.:.||.|.|:|..|:|||||:|...|||:...|..:|..|.|:|.|:|||||
Zfish    58 SSTEMTGG----GGKKKRSRAAFTHLQVLELEKKFSRQRYLSAPERTHLASALHLTETQVKIWFQ 118

  Fly   416 NRRMKWKK 423
            |||.|.|:
Zfish   119 NRRYKTKR 126

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	28/51 (55%)
nkx3-1	NP_001373254.1	COG5576	15..>136	CDD:227863	44/124 (35%)
nkx3-1	NP_001373254.1	Homeobox	72..126	CDD:395001	28/53 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910