DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and crx

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_001016021.1	Gene:	crx / 548775	XenbaseID:	XB-GENE-478452	Length:	290	Species:	Xenopus tropicalis

Alignment Length:	171	Identity:	43/171 - (25%)
Similarity:	66/171 - (38%)	Gaps:	24/171 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   367 KRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKLPNTK 431
            :|:||.:||.|:..||..|...||.....|.|:|..:.|.|.::::||:|||.|.::
Frog    39 RRERTTFTRAQLDILEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ-------- 95

  Fly   432 NVRKKTVDANGNPTPVAKKPTKRAASKKQQQAQQQQQSQQQQTQQTPVMNECIRSD-----SLES 491
              :::.......|.|..||.:....:..:.....|.......|..||.........     |:..
Frog    96 --QQQQSTGQAKPRPAKKKTSPARETNSEASTNGQYSPPPPGTAVTPSSTASATVSIWSPASISP 158

  Fly   492 IGD---------VSSSLGNPPYIPAAPETTSSYPGSQQHLS 523
            |.|         :..|.|.|.....||..|.||.||..:.:
Frog   159 IPDPLSAATTPCMQRSAGYPMTYSQAPAYTQSYGGSSSYFT 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	21/51 (41%)
crx	NP_001016021.1	Homeobox	42..94	CDD:395001	21/51 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	93..144		8/60 (13%)
		TF_Otx	154..236	CDD:397546	13/46 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910