Protein Alignment Dfd and PAX6

DIOPT Version :9

• Sequence 1: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001355839.1
• Gene: PAX6 / 5080
• HGNCID: 8620
• Length: 503
• Species: Homo sapiens
• Alignment Length: 539
• Identity: 110/539 - (20%)
• Similarity: 179/539 - (33%)
• Gaps: 188/539 - (34%)

  Fly    95 NPHSHSHSHTHSLPHHHSNS-----AISGHHQASA-----GGYSSNYANATPPSHPH--SHPHAH 147
            ||.:.|.|. |:.....|::     |::|.::..|     ||.:..:...:|.|..|  :..|:.
Human    25 NPAAPSQSQ-HAEQGGRSSAAEIKRAVAGANRLPALSLTCGGRTCLWLKPSPGSDSHVCTGGHSG 88

  Fly   148 PHQSLGYYVHHAP----------EFISAGAVHSDPTNGYGPAANVPNTSNGGGGGGSGAVLGGGA 202
            .:|..|.:|:..|          |...:||...|       .:.:...||             |.
Human    89 VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCD-------ISRILQVSN-------------GC 133

  Fly   203 VGGSANGYYGGYGGGYGTANGSVGSTHSQGHSPH-------SQMMDLPLQCSSTEPPTNTALGLQ 260
            |......||         ..||:......|..|.       |::.....:|     |:..|..::
Human   134 VSKILGRYY---------ETGSIRPRAIGGSKPRVATPEVVSKIAQYKREC-----PSIFAWEIR 184

  Fly   261 ELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSENDDMSEE---DRLML--------------- 307
            :..|.......:.:|:...:..:   ||  ::.||...|..:   |:|.:
Human   185 DRLLSEGVCTNDNIPSVSSINRV---LR--NLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWY 244

  Fly   308 -----------DRSPDELGSNDNDDDLGDS--DSDEDLMAETTDGERIIYPWMKKIHVAGVANGS 359
                       |....:.|..:|.:.:..:  ||||                         |...
Human   245 PGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDE-------------------------AQMR 284

  Fly   360 YQPGMEPKRQRTAYTRHQILELEKEF---HYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKW 421
            .|...:.:|.||::|:.||..|||||   ||.....|.|   :|..:.|.|.:|::||.|||.||
Human   285 LQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARER---LAAKIDLPEARIQVWFSNRRAKW 346

  Fly   422 KKDNKLPNTKNVRKKTVDANGNPTPVAKKPTKRAASKKQQQAQQQQQSQQQQTQQTPVMNECIRS 486
            :::.||.|.:.      .|:..|:.:   |...:.|....|...|        ..|||.:  ..|
Human   347 RREEKLRNQRR------QASNTPSHI---PISSSFSTSVYQPIPQ--------PTTPVSS--FTS 392

  Fly   487 DSLESIGDVSSSL----------------GNPPYIPAAPETTSSY-------------------- 515
            .|:  :|...::|                .|.|..|..|..||||
Human   393 GSM--LGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTP 455

  Fly   516 PGSQQHLSNNNNNGSGNNN 534
            |..|.|:::.....||..:
Human   456 PHMQTHMNSQPMGTSGTTS 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	24/54 (44%)
PAX6	NP_001355839.1	PAX	85..209	CDD:128645	25/160 (16%)
		Homeobox	295..348	CDD:395001	25/55 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910