DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dfd and hoxc8a

DIOPT Version :9

Sequence 1:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_001005771.1	Gene:	hoxc8a / 449648	ZFINID:	ZDB-GENE-990415-114	Length:	250	Species:	Danio rerio

Alignment Length:	161	Identity:	59/161 - (36%)
Similarity:	86/161 - (53%)	Gaps:	21/161 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   307 LDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERIIYPWMKKIHVAGVANGSYQPGMEPKRQRT 371
            |.:.||...||..:...|.....::      ....:::|||:. |..|..||           |.
Zfish   108 LAQYPDCKSSNSTNPGEGQGHLSQN------SSPSLMFPWMRP-HAPGRRNG-----------RQ 154

  Fly   372 AYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDN---KLPNTKNV 433
            .|:|:|.|||||||.:|.||||:||||::|.|.|:|||:|||||||||||||:|   |.|..:..
Zfish   155 TYSRYQTLELEKEFLFNPYLTRKRRIEVSHALSLTERQVKIWFQNRRMKWKKENNKDKFPGQRGE 219

  Fly   434 RKKTVDANGNPTPVAKKPTKRAASKKQQQAQ 464
            .:...:..||....|::...:...:|::..:
Zfish   220 AEAEAEEEGNEDGEAEEGEDKETEEKEESKE 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	36/51 (71%)
hoxc8a	NP_001005771.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	112..152		10/46 (22%)
		Antp-type hexapeptide. /evidence=ECO:0000255	138..143		2/4 (50%)
		Homeobox	153..205	CDD:278475	36/51 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	206..250		8/43 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810